Protein Structure Prediction: Methods and Protocols (Methods in Molecular Biology) - Hardcover

Webster, David M.

Hardcover

ISBN 10: 0896036375 ISBN 13: 9780896036376

Publisher: Human, 2000

Synopsis

World-class investigators detail their most successful methods-and the theory behind them-for delineating the shape, form, and function of proteins. The protocols range from basic to advanced and include sequence alignment, the prediction of transmembrane protein structure, and the development of suitable folding potentials. There are also techniques for receptor site prediction, the identification of motifs and domains, the comparative modeling of proteins, the docking of peptides and ligands, and ab initio approaches to protein loop and side-chain prediction. Comprehensive, accessible, and highly practical, Protein Structure Methods and Protocols offers protein researchers, structural biologists, and other investigators a critical synthesis of the latest research results, as well as the vital guidance needed to understand the structure and interaction of proteins and peptides.

About this title

Review

"The organization of this book is excellent. Eighteen chapters lead the reader through the entire process....Many of the authors are, in fact, the developers of some commonly used methods and offer a first-hand introduction to their software....The emphasis is on providing a practical handbook...most chapters contain detailed tutorials and worked-through examples that give a real-life flavor to the explanations."- Journal of American Chemical Society

"The book is a collection of 18 review articles, many written by distinguished experts in their field, providing an overview of the major aspects of protein structure prediction. About half of the articles deal with specific software packages, many of which are free to academic users, where the author of the software discussed....a useful reference to address for anyone thinking of dipping their toes into this exciting field." - Biochemistry and Molecular Biology Education

Edition details

• Publisher: Human
• Publication date: 2000
• Language: English
• ISBN 10: 0896036375
• ISBN 13: 9780896036376
• Binding: Hardcover
• Edition number: 1