Transgenic Mouse: Methods and Protocols (Methods in Molecular Biology, Vol. 209) - Hardcover

Marten H. Hofker

Hardcover

ISBN 10: 0896039153 ISBN 13: 9780896039155

Publisher: Humana Press, 2002

Synopsis

This work is for geneticists and molecular and cell biologists. It provides step-by-step mouse methods and hints on how to deal with a transgenic mouse project.

About this title

From the Back Cover

The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful. In Transgenic Mouse Methods and Protocols, Second Edition, expert research explore current advances in the field through detailed laboratory protocols. Chapters provide a general introduction outlining how to deal with mice and how to generate transgenic mouse models, explore the generation of conditional and induced knockout and transgenic mice, and offer alternative routes to studying gene function in mice. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and state-of-the-art, Transgenic Mouse Methods and Protocols, Second Edition is the ideal guide for all researchers interested in the latest information about the production and analysis of transgenic and knockout mice.

Review

"...highly recommendable to cyto- and histochemist researchers, since they can easily find the way to enrich the instrumentarium of their own conceptual tools." - European Journal of Histochemistry

Edition details

• Publisher: Humana Press
• Publication date: 2002
• Language: English
• ISBN 10: 0896039153
• ISBN 13: 9780896039155
• Binding: Hardcover
• Edition number: 1