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Pharmacokinetic allometric scaling is a very useful tool for the selection of first-in-human dose in drug development. This is the first book ever written on the interspecies pharmacokinetic scaling consists of 393 pages and is an ideal resource for pharmaceutical scientists, pre-clinical and clinical pharmacologists, physiologists, biochemists, toxicologists, environmental health scientists, veterinarians, and biologists in academic and industry.
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- PublisherPine House Pub
- Publication date2005
- ISBN 10 0976643804
- ISBN 13 9780976643807
- BindingHardcover
- Edition number1
- Number of pages393
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Interspecies Pharmacokinetic Scaling: Principles And Application of Allometric Scaling
Published by
Pine House Pub
(2005)
ISBN 10: 0976643804
ISBN 13: 9780976643807
Used
Hardcover
Quantity: 1
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Book Description Hardcover. Condition: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less 1.45. Seller Inventory # G0976643804I3N00
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Interspecies Pharmacokinetic Scaling: Principles And Application of Allometric Scaling
Published by
Pine House Pub
(2005)
ISBN 10: 0976643804
ISBN 13: 9780976643807
Used
Hardcover
Quantity: 1
Seller:
Rating
Book Description Hardcover. Condition: Very Good. Minor shelf wear, binding tight, pages clean and unmarked.cbout the book: Interspecies Pharmacokinetic Scaling: Allometric Principles and Applications provides a detailed insight into the allometric scaling of pharmacokinetics (PK) of xenobiotics. The book: ? Provides readers with a practical view of allometric scaling and its usefulness in drug development ? Provides step by step procedures to scale PK parameters from laboratory animals to humans and offers several approaches for the selection of the first-in-human dose based on predicted PK parameters ? Discusses how to scale PK parameters from laboratory animals to large animals and how to select animal dose based on predicted PK parameters ? Discusses how to predict maximum tolerated dose (MTD) of anticancer drugs from animals to humans and how to select a dose escalation scheme ? Refutes many wrong and outdated views in allometric scaling and provides a fresh and practical look into the allometric scaling of pharmacokinetics This book is an ideal resource for pharmaceutical scientists, pre-clinical and clinical pharmacologists, toxicologists, physiologists, biochemists, biologists, veterinarians, and environmental health scientists in academic and industry. The book is also of immense value to clinical pharmacists and medical center-based clinicians. The book is also helpful to graduate students in schools of pharmacy and health sciences. Seller Inventory # 231209004
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