Spatial Genome Organization: Methods and Protocols (Methods in Molecular Biology, 2532) - Hardcover

Book 141 of 382: Methods in Molecular Biology
 
9781071624968: Spatial Genome Organization: Methods and Protocols (Methods in Molecular Biology, 2532)
Hardcover
ISBN 10: 1071624962 ISBN 13: 9781071624968
Publisher: Humana, 2022

Synopsis

This detailed volume explores a variety of cutting-edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi-C approaches, sequencing-based approaches to assess nuclear environment, as well as single-cell technologies to better characterize the heterogeneity and dynamics of nuclear architectures and approaches to visualize them by microscopy. Finally, in order to be able to ask functional questions about the role of spatial chromatin organization in genomic control, the last section provides methods for acute manipulations of chromatin architecture. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and practical, Spatial Genome Organization: Methods and Protocols is an ideal resource for researchers searching for the best techniques to address their own specific research questions.

"synopsis" may belong to another edition of this title.

From the Back Cover

This detailed volume explores a variety of cutting-edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi-C approaches, sequencing-based approaches to assess nuclear environment, as well as single-cell technologies to better characterize the heterogeneity and dynamics of nuclear architectures and approaches to visualize them by microscopy. Finally, in order to be able to ask functional questions about the role of spatial chromatin organization in genomic control, the last section provides methods for acute manipulations of chromatin architecture. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and practical, Spatial Genome Organization: Methods and Protocols is an ideal resource for researchers searching for the best techniques to address their own specific research questions.

"About this title" may belong to another edition of this title.

Publisher
Humana
Publication date
2022
Language
English
ISBN 10 
1071624962
ISBN 13 
9781071624968
Binding
Hardcover
Edition number
1
Number of pages
344
Editor
Sexton Tom

Other Popular Editions of the Same Title

9781071624999: Spatial Genome Organization: Methods and Protocols (Methods in Molecular Biology)

Featured Edition

ISBN 10:  1071624997 ISBN 13:  9781071624999
Publisher: Humana, 2023
Softcover