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Synopsis
This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.
Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics.
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From the Back Cover
This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.
Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics.
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics. 316 pp. Englisch. Seller Inventory # 9781071654750
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Buch. Condition: Neu. Gapmers | Methods and Protocols | Toshifumi Yokota (u. a.) | Buch | Methods in Molecular Biology | xii | Englisch | 2026 | Humana | EAN 9781071654750 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Seller Inventory # 138076071
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics. Seller Inventory # 9781071654750
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Gapmers: Methods And Protocols
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