Guide to Fluorine NMR for Organic Chemists - Hardcover

Dolbier Jr., William R.

Hardcover

ISBN 10: 111883108X ISBN 13: 9781118831083

Publisher: Wiley, 2016

Synopsis

Following its well-received predecessor, this book offers an essential guide to chemists for understanding fluorine in spectroscopy. With over 1000 compounds and 100 spectra, the second edition adds new data – featuring fluorine effects on nitrogen NMR, chemical shifts, and coupling constants.

·    Explains how to successfully incorporate fluorine into target molecules and utilize fluorine substituents to structurally characterize organic compounds
·    Includes new data on nitrogen NMR, focusing on N-15, to portray the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants
·    Expands on each chapter from the first edition with additional data and updated discussion from recent findings
·    "The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily." – Angewandte Chemie review of the first edition, 2010

About this title

From the Back Cover:

"The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily." – Angewandte Chemie review of the first edition, 2010

Following its successful first edition, Guide to Fluorine NMR for Organic Chemists provides an unparalleled guide to fluorine NMR and the impact of fluorine substituents on proton and carbon NMR spectra. The author enhances each chapter with additional data and updated discussion of recent findings to continue helping working chemists overcome the challenges associated with the synthetic methodologies of fluorinated compounds.

After a thorough introduction of fluorinated compounds, chapters in the text cover:

·An overview of fluorine NMR

·The single fluorine substituent

·The CF2 group

·The trifluoromethyl group

·More heavily fluorinated compounds

·Compounds and substituents with fluorine directly bound to heteroatoms

Coverage ranges from those compounds containing only a few fluorinated substituents, typically employed in pharmaceutical and agricultural applications, to more heavily fluorinated compounds. Furthermore, the second edition features new discussion of nitrogen NMR and the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants. Altogether, this information enables the effective use of these increasingly popular spectroscopic techniques to accurately characterize compounds that contain fluorine.

Featuring NMR data for more than 1,000 specific compounds and including more than 100 exemplary spectra, Guide to Fluorine NMR for Organic Chemists gives the working chemist and advanced student an essential tool for understanding cutting-edge NMR techniques and interpreting the resulting spectroscopic data.

About the Author:

William R. Dolbier, Jr., is the Col. Allen R. and Margaret G. Crow Professor of Chemistry at the University of Florida. He received his BS in chemistry from Stetson University in 1961 and his PhD in organic chemistry from Cornell University in 1965. Following a postdoctoral appointment at Yale University, he joined the faculty at the University of Florida in 1966. Professor Dolbier was the recipient of the 2000 American Chemical Society (ACS) Award for Creative Work in Fluorine Chemistry, and is a past member of the Executive Committee of the Fluorine Division of the ACS.

About this edition

• Publisher: Wiley
• Publication date: 2016
• ISBN 10: 111883108X
• ISBN 13: 9781118831083
• Binding: Hardcover
• Edition number: 2
• Number of pages: 368