Items related to The Pathology of Tumours
This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1916 edition. Excerpt: ...there is a certain amount of independent growth on the part of the tumours, for they often are raised to some extent above the surface, and their deeper margins are fairly sharply defined; moreover, a microscopical examination shows nearly always some compression of the liver cells at the periphery of the nodule, distinct evidence of an expansive growth. But it is only in the more slowly growing forms that independent or expansive growth is at all marked. With a higher degree of malignancy the great mass of the tumour results from the invasion and destruction of the adjacent structures; indeed, we find the stroma in the central parts lagging behind the more active parenchyma, which, deprived of the necessary nourishment, dies. It is to the central death of the cells, with the subsequent slow replacement by fibrous tissue, that the umbilication of superficial tumours, an important sign in the differential diagnosis between neoplasms and inflammatory formations such as gummata, is due. Whatever its origin may be, whether intrinsic or extrinsic, we find the stroma varying considerably in character in different classes of tumours. Its composition is always quite simple, consisting only of fibrous connective tissue and blood vessels; but the amount of formed fibrous tissue, the number and activity of the fibroblasts, and the richness of the vascular supply all differ within very wide limits. As a rule, we find an abundance of stroma in the carcinomata derived from epithelium which normally possesses a rich connective tissue investment, and vice versa. Thus, the breast is an organ containing a large quantity of connective tissue, and carcinomata of the breast have usually a plentiful well-formed stroma. Again, there is little supporting tissue...
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- PublisherRareBooksClub.com
- Publication date2013
- ISBN 10 115279132X
- ISBN 13 9781152791329
- BindingPaperback
- Number of pages86
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