Blood Substitutes: New Challenges - Softcover

Softcover

ISBN 10: 146128659X ISBN 13: 9781461286592

Publisher: Birkhäuser, 2011

Synopsis

This book is not a "proceedings" volume. Rather the chapters are essays by experts in the field of blood substitutes, invited by the editors to con­ tribute to the 1996 "Current Issues in Blood Substitutes Research and Development" course given in San Diego, March 18-21. The contributors were selected because of their expertise in areas deemed by the editors to be critical to the advancement of the field. The course, as in past years, is heavily influenced by feedback from par­ ticipants, and by research in this and related fields. In addition to the didactic lectures (for which these chapters are the foundation), the course also offers the opportunity for presentation of research reports, progress reports from the various companies currently commercializing products, and round table discussions of selected subjects. Thus, we are grateful to past participants for their helpful comments. Production of a book, especially on a short timeline, is not an easy feat.

About this title

From the Back Cover

Although blood substitutes represent a goal that has been sought for more than a century, their development is now on the cutting edge of biotechnology: beyond biochemistry and molecular biology, these products are being integrated into the larger physiological picture of gas transport that is essential to every living organism. New products will find obvious clinical application, since they overcome many of the problems with blood transfusion, such as the need to crossmatch, storage limitations, and the risk of transmission of infectious disease. As work continues to bring this new class of products to market, discoveries have been made about very basic aspects of how red blood cells work with regard to the exchange of oxygen and carbon dioxide and interactions with molecules such as nitric oxide and carbon monoxide which may mediate contractility of smooth muscle. These new challenges are being met with impressive rapidity as products are readied for testing and introduction into clinical use. As more is understood about the general properties of artificial blood substitutes, attention is focusing on applications which will benefit the most from their availability. This volume is a collection of chapters by researchers currently working in the field of blood substitutes and closely related fields. Each of them focuses on current challenges from a different perspective, from the clinical question, "What is the target?", to detailed descriptions of the interactions with nitric oxide, endotoxin, and carbon dioxide. Included in the volume is a review of the peer-reviewed research published in 1995 and a general discussion of current products and potential clinical applications. Takentogether, these chapters provide an up-to-date picture of this rapidly evolving field.

Review

"This is a serious, comprehensive, authoritative and highly readable textbook on a most relevant and challenging topic the search for blood substitutes."
- Professor Ken Taylor, British Heart Foundation Professor of Cardiac Surgery, University of London
and Director of Cardiac Services, Hammersmith Hospital, London, UK

"If you are interested in this field, get this book."
- Doody's 3 Star Review by Valerie L. Ng, PhD, MD, Alameda County Medical Center/Highland Hospital (2006)
"This is a serious, comprehensive, authoritative and highly readable textbook on a most relevant and challenging topic the search for blood substitutes."
- Professor Ken Taylor, British Heart Foundation Professor of Cardiac Surgery, University of London
and Director of Cardiac Services, Hammersmith Hospital, London, UK

"As an introduction to the field, this book is outstanding."
- John R. Hess MD, MPH, FACPa, University of Maryland Medical Center for TRANSFUSION MEDICINE REVIEWS (2006)

"If you are interested in this field, get this book."
- Doody's 3 Star Review by Valerie L. Ng, PhD, MD, Alameda County Medical Center/Highland Hospital (2006)

"This is a serious, comprehensive, authoritative and highly readable textbook on a most relevant and challenging topic the search for blood substitutes."
- Professor Ken Taylor, British Heart Foundation Professor of Cardiac Surgery, University of London
and Director of Cardiac Services, Hammersmith Hospital, London, UK

About this edition

• Publisher: Birkhäuser
• Publication date: 2011
• ISBN 10: 146128659X
• ISBN 13: 9781461286592
• Binding: Paperback
• Number of pages: 222
• Editor: Winslow Robert M., Vandegriff Kim D., Intaglietta Marcos