Stereoselective Synthesis: (Part H) Studies in Natural Products Chemistry - Softcover

Softcover

ISBN 10: 1483177432 ISBN 13: 9781483177434

Publisher: Elsevier, 2013

Synopsis

Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines. Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes. The book can provide useful information to chemists, biologists, students, and researchers.

Edition details

• Publisher: Elsevier
• Publication date: 2013
• Language: English
• ISBN 10: 1483177432
• ISBN 13: 9781483177434
• Binding: Paperback
• Number of pages: 540
• Editor: Atta-ur-Rahman Atta-ur-Rahman