Over the past 50 years, scientists have made incredible progress in the application of genetic research to human health care and disease treatment. Innovative tools and techniques, including gene therapy and CRISPR-Cas9 editing, can treat inherited disorders that were previously untreatable, or prevent them from happening in the first place. You can take a DNA test to learn where your ancestors are from. Police officers can use genetic evidence to identify criminals―or innocents. And some doctors are using new medical techniques for unprecedented procedures.
Genomics: A Revolution in Health and Disease Discovery delves into the history, science, and ethics behind recent breakthroughs in genetic research. Authors Whitney Stewart and Hans Andersson, MD, present fascinating case studies that show how real people have benefitted from genetic research. Though the genome remains full of mysteries, researchers and doctors are working hard to uncover its secrets and find the best ways to treat patients and cure diseases. The discoveries to come will inform how we target disease treatment, how we understand our health, and how we define our very identities.
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Hans C. Andersson, MD, is the Karen Gore Chair of Human Genetics and director of the Hayward Genetics Center at the Tulane University Medical School, where he directs the Biochemical Genetics Lab. Following fellowship training in clinical genetics and cell biology at the National Institutes of Health and University of Gottingen, Germany, Andersson achieved American Board of Medical Genetics certification in clinical genetics and clinical biochemical/molecular genetics and American Board of Pediatrics certification in pediatrics. His research has elucidated clinical features and pathophysiology of inherited metabolic genetic disorders, especially in lysosomal storage disorders. He leads the major regional referral center for such diseases in the Gulf South and is a member of the board for the International Collaborative Gaucher Group and a member of numerous national societies including the Society of Pediatric Research and the Society of Inherited Metabolic Diseases.
Whitney Stewart is an award-winning author of fiction and nonfiction books for kids―for toddlers to young adult. Her research has taken her to Nepal with Sir Edmund Hillary, to India to interview the Dalai Lama, and to China's Great Wall. She also teaches mindfulness and meditation and lives in New Orleans.
Gr 8 Up-This unique look at the history and impact of genomics will excite students eager to learn more about the human genome. The text goes beyond buzzwords and popular science ideas to explore related key concepts, such as Sanger sequencing and gene therapy. Real cases are included and add depth by addressing the science behind genetic testing and the people directly impacted by it. The text clearly addresses the changing nature of scientific understanding for younger readers. Stewart and Andersson chronicle the natural progression of changes applied to academic beliefs about genes and the methodologies used to study them. Commendably, the authors discuss the accomplishments of overlooked researchers, the reality of patients with inherited disorders, and other ethical issues connected to the misapplications of gene-related studies. They are honest and respectful of readers' intelligence in a way that is refreshing in an area of nonfiction that can sometimes be esoteric. VERDICT An excellent bridge between real-world technology applications of biotechnology and what students learn in their biology classrooms.-Lisa Bosarge, Enoch Pratt Free Lib., Baltimoreα(c) Copyright 2011. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.
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