Aging is not only an important biological issue but also an important social and emotional issue for the increasing number of elderly in industrialized countries. This book covers a wide range of complementary research areas, including work at the molecular and cellular levels, theories of aging, the molecular basis of the loss of homeostatic maintenance mechanisms, lower and higher model organisms, the genetics of human longevity, clinical and molecular aspects of age-related diseases, and integrated systems such as brain and immune system aging. The purspose of the research presented here is to understand the molecular mechanisms of aging and to help prevent age-related diseases.
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Olivier Toussaint is with the University of Namur, Belgium. Heinz Osiewacz is with the University of Frankfurt, Germany. Gordon Lithgow is with the University of Manchester, U.K. Christine Brack is with the University of Basel, Switzerland.
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