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Synopsis
The need to screen targets faster and more efficiently, coupled with advances in parallel and multiplex chemical synthesis, has contributed to the increasing use of multiwell assays for drug discovery. The Handbook of Assay Development in Drug Discovery is a reference that describes the complete armament of tools currently available for performing various assay techniques.
Featuring contributions from assay developers in the pharmaceutical and vendor communities, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. The handbook describes biochemical assay classes as well as non-class specific assay development for cell-based assays. It covers a wide range of target classes―including kinases, proteases, nuclear receptors, and GPCRs―and describes currently employed methods and assay types, such as radioligand binding assays, image analysis assays, enzyme fragment complementation, and bioluminescent and fluorescent-based assays.
Designed as a guide to running an assay from start to finish, the Handbook of Assay Development in Drug Discovery is an ideal bench top companion for discovery researchers, laboratory managers, academics, and other scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation in the pharmaceutical and biotechnology industries.
Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.
"synopsis" may belong to another edition of this title.
Review
To be as advanced as possible, Dr. Minor has had individual chapters written by experts from equipment vendors (GE, PerkinElmer); pharmaceutical companies (J&J, Merck, Lilly), government (NIH) and more. These individual chapters describe in practical terms what these organizations have developed.
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- PublisherCRC Press
- Publication date2006
- ISBN 10 1574444719
- ISBN 13 9781574444711
- BindingHardcover
- LanguageEnglish
- Edition number1
- Number of pages482
- EditorMinor Lisa K.
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Handbook of assay development in drug discovery. Edited by Lisa K. Minor.
Published by
Boca Raton, CRC/Taylor & Francis, ., 2006
ISBN 10: 1574444719
ISBN 13: 9781574444711
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1 online resource (464 pages) : illustrations (some color). Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Drug discovery series; 5. Sprache: Englisch. Seller Inventory # 45032HB
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Handbook of Assay Development in Drug Discovery (Drug Discovery Series)
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Handbook of Assay Development in Drug Discovery (Drug Discovery Series)
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Handbook of Assay Development in Drug Discovery
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Handbook of Assay Development in Drug Discovery
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The Handbook of Assay Development in Drug Discovery describes all the tools currently available for performing various assay techniques. Featuring troubleshooting advice for common problems from experienced assay developers, the vendor community, and scientists in the pharmaceutical industry, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. Designed as a guide to running an assay from start to finish, this is an ideal bench top companion for scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation. Seller Inventory # 9781574444711
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Handbook of Assay Development in Drug Discovery
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