Preclinical Drug Development (Drugs and the Pharmaceutical Sciences) - Hardcover

Hardcover

ISBN 10: 157444882X ISBN 13: 9781574448825

Publisher: CRC Press, 2005

Synopsis

This reference discusses in detail the broad realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology through the regulatory expectations that support clinical trials. Providing chapters on pharmacokinetics, modeling and simulation, formulation and routes of administration, toxicity evaluations, the assessment of drug absorption and metabolism, and interspecies scaling, this guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.

About this title

Review

...an interesting and effective survey of major issues in preclinical development, and of the experimental approaches and models applied to those issues.
-Doody's Reviews

...covers the general elements of preclinical drug development and introduces the reader to these scientific disciplines.
-European Journal of Pharmaceutics and Biopharmaceutics

...provides a useful and comprehensive overview of the diverse disciplines involved in preclinical drug development citing real examples and case studies to emphasi[z]e regulatory requirements.

--British Toxicology Society

Edition details

• Publisher: CRC Press
• Publication date: 2005
• Language: English
• ISBN 10: 157444882X
• ISBN 13: 9781574448825
• Binding: Hardcover
• Edition number: 1
• Number of pages: 600
• Editor: Rogge Mark C., Taft David R.