Synopsis
Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).
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From the Back Cover
The immunostimulatory prospects of bacterial DNA have attracted the interest and attention of scientists and physicians and become a major focus in immunobiology and biomedicine. These activities are the product of immunostimulatory DNA sequences (ISS, also known as GpG motifs), which are rare in the mammalian genome. ISS were shown to enhance immunological responses and were used to confer protection to a wide variety of tumors, allergic inflammation, and infections. In Microbial DNA and Host Immunity, leading researchers review the activation of the mammalian immune system by bacterial DNA and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS, the process of cell activation, and potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).
Up-to-date and informative, Microbial DNA and Host Immunity illuminates the immunobiology of bacterial DNA and its promise of powerful new vaccines to provide protective immunity against infections, tumors, and chronic disease.
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Microbial DNA and Host Immunity
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Hardcover. Condition: Fine. 1588290220. Pharmaceutical company library, laminated, pictorial board hardcover. Lending record shows this book has never been borrowed. 428 pages, index, illustrated with charts, tables and diagrams. Reviews the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and considers the applications of ISS in clinical medicine. The authors survey findings concerning the receptor-recognition and signalling pathways triggered by ISS, the process of cell activation, and the potential vaccination strategies using ISS. Applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).Contents as new, clean, tight and bright. Book. Seller Inventory # 027156
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MICROBIAL DAN AND HOST IMMUNITY
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Microbial DNA and Host Immunity
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Humana Press Inc, Totowa, New Jersey, USA, 2002
ISBN 10: 1588290220
ISBN 13: 9781588290229
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Hardcover. Condition: New. No Jacket. 1st Edition. Brand New. First Edition / First Print (number line on copyright page 10 9 8 7 6 5 4 3 2 1). Hardback copy in pictorial boards, no dustjacket as issued. 408pp. Graphs throughout. Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis). (24/1). Seller Inventory # ABE-1638975697716
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