After an interesting in-depth historical perspective, this book reviews recent scientific advances in molecular genetics and biology of chronic lymphocytic leukemia, and discusses clinical aspects of the disease, focusing on diagnosis, prognosis, treatment options, and complications. A final chapter addresses familial and juvenile cases. DNLM: Leukemia, Lymphocytic, Chronic.
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Chronic lymphocytic leukemia (CLL) is the second most frequently encountered leukemia in North America and Europe, and the object of considerable research and treatment. In Chronic Lymphocytic Leukemia: Molecular Genetics, Biology, Diagnosis, and Management, prominent physicians and researchers from the leading medical centers in the United States and Europe critically review the latest scientific advances in our understanding of the molecular genetics and biology of CLL and apply them to its best management. Their comprehensive reviews of the clinical aspects of CLL focus on diagnosis, prognosis, multifaceted treatment options, and complications. Among the diverse treatments considered are chemotherapy, autologous and allogeneic transplantations, monoclonal antibody therapy, immunotoxin therapy, gene therapy, and several promising new therapeutic strategies. Familial and juvenile chronic lymphocytic leukemia are also discussed.
Cutting-edge and clinically focused, Chronic Lymphocytic Leukemia: Molecular Genetics, Biology, Diagnosis, and Management offers today's hematologists and oncologists the opportunity to update their clinical knowledge and sort out the range of available therapies to provide optimal patient care.
This book, edited by Guy B. Faguet a retired professor of medicine at the Medical College of Georgia in Augusta, GA, was contributed by 43 chronic lymphocytic leukemia experts; 23 from the United States and 19 from Europe. The resulting 23 chapters were organized into 7 sectional themes covering the natural history of CLL, its biology and genetics, its clinical aspects (diagnosis, prognosis, treatment, and complications), and familial and juvenile CLL.For more details, please visit Dr. Faguet's website: faguet.net --Editor
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