Pain Research: Methods and Protocols (Methods in Molecular Medicine) - Hardcover

Z. David Luo

Hardcover

ISBN 10: 1588291030 ISBN 13: 9781588291035

Publisher: Humana Press, 2004

Synopsis

Noted scientists provide step-by-step methods and protocols for the study of pain transduction. They cover everything from animal models resembling the pathological conditions of pain transduction, and protocols to understand the interactions among pain transducers and mediators at the molecular level. The authors present a variety of multidisciplinary approaches to dissecting the molecular mechanisms of pain transduction making this essential for all pain researchers.

About this title

From the Back Cover

Despite significant advances in molecular biology techniques and in our understanding of the physiology and the behavioral pharmacology of pain transduction, effective, target-specific therapeutic agents for chronic pain are still lacking. In Pain Research: Methods and Protocols, leading researchers who have first-hand experience describe, in step-by-step detail, diverse and novel techniques for dissecting the molecular mechanisms of pain transduction. These readily reproducible methods employ a variety of multidisciplinary approaches ranging from animal pain models and single neutron selection to in vitro single-cell mRNA amplification. The collection includes not only standard, cutting-edge methods, but also novel techniques only recently applied to pain research. The protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Versatile and easy-to-use, Pain Research: Methods and Protocols offers today's pain researchers in academic and pharmaceutical laboratories powerful tools to unravel the cellular and molecular complexity of pain transduction and set the stage for the next generation of pain medications.

Review

From the reviews of the second edition:

“This second edition of Pain Research – Methods and Protocols is an excellent compendium of chapters outlining the most current techniques used to study the neurobiology of pain. ... Pain Research – Methods and Protocols is aimed not only at the novice researcher with little experience in the field but also at bringing new techniques and approaches to the pain research community as a whole. The clear organizational structure of the text makes this a highly achievable goal.” (Bradley Kerr, Canadian Journal of Anesthesia/Journal Canadien d'anesthésie, Vol. 60, January, 2013)

Edition details

• Publisher: Humana Press
• Publication date: 2004
• Language: English
• ISBN 10: 1588291030
• ISBN 13: 9781588291035
• Binding: Hardcover
• Edition number: 1
• Number of pages: 320