Beginning from an engineering perspective and written for engineering students, this textbook presents applications in systems bioinformatics, the intersection of systems biology and bioinformatics. The approach adopted by the editors (both of Harvard Medical School) is to match familiar engineering ideas, such as analysis, design, and reverse engineering with their applications in systems bioinformatics. Thus, a section on signal processing addresses biological signal processing and signal processing methods for mass spectrometry, a section on control and systems explores modeling cellular networks, and a section on probabilistic data networks and communications contains chapters on topological analysis of biomolecular networks and on Bayesian networks for genetic analysis. Other topics addressed include fundamentals of design for synthetic biology, applied cellular engineering, DNA/RNA sequence hybridization, biomolecular computing and cryptography, and chemotaxis. The CD-ROM contains a variety of computer programs for data analysis, modeling, and other purposes. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)
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Gil Alterovitz is on the faculty at Harvard Medical School, where he is engaged in research that applies engineering systems approaches to biomedical problems. Dr. Alterovitz is a part of the Children's Hospital Informatics Program at the Harvard/MIT Division of Health Sciences and Technology. He is also affiliated with the MIT Department of Electrical Engineering and Computer Science and Harvard University, where he is teaching a class on the topic of systems bioinformatics this year. He earned his Ph.D. in Electrical and Biomedical Engineering at MIT.
Marco F. Ramoni is an assistant professor of Pediatrics and Medicine at Harvard Medical School and an assistant professor of Health Sciences and Technology at Harvard and the Massachusetts Institute of Technology (MIT). He is also associate director of Bioinformatics at the Harvard Partners Center for Genetics and Genomics (HPCGG) and faculty member at the Children's Hospital Informatics Program (CHIP). He received his Ph.D. in Biomedical Engineering from the University of Pavia, Italy.
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