Brain Development and Sexual Orientation (Colloquium Series on the Developing Brain) - Softcover

Balthazart, Jacques

Softcover

ISBN 10: 1615044582 ISBN 13: 9781615044580

Publisher: Morgan & Claypool Life Sciences, 2012

Synopsis

Sexual orientation (homo- vs. heterosexuality) is one of many sex differences observed in humans. Sex differences can result from differential postnatal experiences (interaction with parents, environment) or from biological factors (hormones and genes) acting pre- or postnatally. The first option is often favored to explain sexual orientation although it is supported by little experimental evidence. In contrast, many sexually differentiated behaviors are organized during early life by an irreversible action of sex steroids. In particular, the preference for a male or female sex partner is largely determined in rodents by embryonic exposure to sex steroids. The early action of these steroids also seems to affect sexual orientation in humans. Indeed, clinical conditions associated with major endocrine changes during embryonic life often result in an increased incidence of homosexuality. Furthermore, multiple sexually differentiated behavioral, physiological, or even morphological traits that are known to be organized by prenatal steroids, at least in animals, are significantly different in homo- and heterosexual populations. Thus, prenatal endocrine (or genetic) factors seem to influence significantly human sexual orientation even if a large fraction of the variance remains unexplained to date. The possible interaction between biological factors acting prenatally and postnatal social influences remains to be investigated.

Table of Contents: Introduction and Definitions / Sex Differences in Animals and Men / The Origins of Human Sex Differences / How Can Effects of Biological Factors on Sexual Orientation Be Studied in Humans? / Endocrine Control of Sex Differences / Organizational Effects of Steroids on Sex Partner Preference in Animals / An Endocrine Model of Human Homosexuality / Sex Steroids Modulate Sexual Motivation during Adulthood in Humans . . . But Not Sexual Orientation / The Organizational Role of Steroids on Sexual Orientation: Analysis of Clinical Cases / Sex Differences Not Related to Sexual Activity Suggest an Atypical Differentiation in Homosexual Subjects / Brain Differences Associated with Sexual Orientation / The Origin of Endocrine Differences Between Embryos / Is There a Role for Postnatal Experiential Factors? / Conclusions / References / Author Biography

Edition details

• Publisher: Morgan & Claypool Life Sciences
• Publication date: 2012
• ISBN 10: 1615044582
• ISBN 13: 9781615044580
• Binding: Paperback
• Language: English
• Number of pages: 132