Signal Transduction: Principles, Pathways, and Processes - Softcover

Cantley, Lewis; Hunter, Tony; Sever, Richard; Thorner, Jeremy

Softcover

ISBN 10: 1621821811 ISBN 13: 9781621821816

Publisher: Cold Spring Harbor Laboratory Press, 2013

Synopsis

Cells must respond to a wide variety of signals. These include hormones, growth factors, morphogens, and environmental stress, as well as signals from internal regulators and checkpoints. A complex network of signal transduction pathways within the cell ensures that these signals are relayed to the correct molecular targets and that the cell responds appropriately.

This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. Taking a novel approach, it first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function.

The book is essential reading for students learning about signal transduction for the first time. It will also be a vital reference for all cell, molecular, and developmental biologists and pharmacologists, neurobiologists, and immunologists studying processes regulated by cell signaling.

About this title

About the Author

Lewis C. Cantley is an American cell biologist and biochemist who has made significant advances to the understanding of cancer metabolism.

Edition details

• Publisher: Cold Spring Harbor Laboratory Press
• Publication date: 2013
• Language: English
• ISBN 10: 1621821811
• ISBN 13: 9781621821816
• Binding: Paperback
• Edition number: 1
• Number of pages: 452