Items related to Addiction, Second Edition (Perspectives CSHL)

9781621823506: Addiction, Second Edition (Perspectives CSHL)
Hardcover
ISBN 10: 1621823504 ISBN 13: 9781621823506
Publisher: Cold Spring Harbor Laboratory Press, 2020

Synopsis

Addiction to psychoactive drugs found in cigarettes, alcoholic drinks, and opioid analgesics is a severe problem for society. Events associated with addiction-drug abuse, dependence, withdrawal, and relapse-involve complex neurobiological changes in the brain. To develop effective long-term treatment strategies for substance use disorders, a more complete understanding of these brain changes is needed.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine provides a comprehensive update on our understanding of the biological basis of and treatment strategies for addiction to psychoactive drugs, with an emphasis on opioids. Contributors examine the molecular targets of alcohol, cannabinoids, nicotine, stimulants, and opioids, the resulting changes to the neurocircuitry, and various genetic, environmental, developmental, and behavioral factors that influence the progression from abuse to addiction and susceptibility to relapse. Advances in animal models of addictive behavior and single-cell strategies to dissect neural circuits are also described.

In addition, the authors review compounds currently used or under development to treat substance use disorders, their pharmacological mechanisms, and challenges related to preclinical testing in animal models. This volume is an indispensable reference for all neuroscientists and those who are interested in understanding and reducing the public health burden of drug addiction.

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About the Author

R. Christopher Pierce is affiliated with Rutgers University Robert Wood Johnson Medical School. Ellen Unterwald is affiliated with Lewis Katz School of Medicine at Temple University. Paul J. Kenny is affiliated with Icahn School of Medicine at Mount Sinai.

"About this title" may belong to another edition of this title.

Publisher
Cold Spring Harbor Laboratory Press
Publication date
2020
Language
English
ISBN 10 
1621823504
ISBN 13 
9781621823506
Binding
Hardcover
Edition number
2
Number of pages
404