The Endoplasmic Reticulum, Second Edition (Perspectives in Biology) - Hardcover

Ferro-Novick, Susan; Rapoport, Tom A.; Schekman, Randy

Hardcover

ISBN 10: 1621824373 ISBN 13: 9781621824374

Publisher: Cold Spring Harbor Laboratory Press, 2023

Synopsis

The endoplasmic reticulum (ER) is a network of membranes that folds, modifies, and transports proteins in eukaryotic cells. It also manufactures lipids and interacts extensively with other organelles, playing essential roles in cell growth and homeostasis.

Written and edited by experts in the field, this new collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive update on advances in our understanding of the structure and multiple functions of the ER. The contributors examine how proteins enter the ER, the biogenesis of membrane proteins, and the role of the ER in protein sorting and quality control. In addition, they discuss how lipids are synthesized and transported to and from the ER.

The volume reviews the architecture of the ER and the ways in which it interacts with other organelles. The consequences for metabolic health and neurodegeneration are also considered. It is thus an essential reference for cell biologists, as well as physiologists and pathologists interested in understanding the role of the ER in disease.

About this title

About the Authors

Susan Ferro-Novick is Professor of Cellular and Molecular Medicine at the University of California, San Diego

Tom A. Rapoport is Professor of Cell Biology at Harvard Medical School

Randy Schekman is Professor of Cell Biology, Development and Physiology at University of California at Berkeley

Edition details

• Publisher: Cold Spring Harbor Laboratory Press
• Publication date: 2023
• Language: English
• ISBN 10: 1621824373
• ISBN 13: 9781621824374
• Binding: Hardcover
• Edition number: 2
• Number of pages: 368