The fields of innate immunity have recently undergone a great transformation. From relatively minor research areas on invertebrates, they have developed into promising fields of investigation these last thirty years. This book aims to show the filiation of results, and thus ideas, concerning innate immunity, since Pasteur (1865), via Metchnikoff (the discoverer of phagocytosis, Nobel Prize) and his collaborators at Pasteur Institute, to end in the works of J. Hoffmann, Nobel Prize 2011. These last team has truly bridged the gap between innate immunity in Invertebrates and in Vertebrates
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Yves Carton is Emeritus Research Director at the CNRS and Vice-President of the Entomological Society of France. He works at the Laboratory Evolution, Genomes, Speciation in the field of Genetics and contributes to the evolution of the history of science.
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Innate immunity is a new branch of immunology, confirmed by three Nobel Prize winners in 2011. It is the first line of defense against pathogens and is in a way the preliminary step of adaptive immunity which occurs later, and only present in vertebrates. This book examines the way in which innate immunity was discovered in invertebrates. As a starting point, it looks at the work of Louis Pasteur on silkworm disease and the findings of Ilya Metchnikov, discoverer of phagocytosis. It also investigates André Paillot, who in 1920 demonstrated the existence of humoral immunity in insects, unrelated to the type of immunity that was initially thought to be present in all vertebrates. Finally, Innate Immunity shows how the group directed by Jules Hoffmann found strong similarities between the innate immunity response of insects and mammals. The discovery of a receptor protein in Drosophila, which is also found in humans, was what led to Jules Hoffmann being awarded the Nobel Prize in 2011. Englisch. Seller Inventory # 9781785483080
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Buch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Innate immunity is a new branch of immunology, confirmed by three Nobel Prize winners in 2011. It is the first line of defense against pathogens and is in a way the preliminary step of adaptive immunity which occurs later, and only present in vertebrates. This book examines the way in which innate immunity was discovered in invertebrates. As a starting point, it looks at the work of Louis Pasteur on silkworm disease and the findings of Ilya Metchnikov, discoverer of phagocytosis. It also investigates André Paillot, who in 1920 demonstrated the existence of humoral immunity in insects, unrelated to the type of immunity that was initially thought to be present in all vertebrates. Finally, Innate Immunity shows how the group directed by Jules Hoffmann found strong similarities between the innate immunity response of insects and mammals. The discovery of a receptor protein in Drosophila, which is also found in humans, was what led to Jules Hoffmann being awarded the Nobel Prize in 2011. Seller Inventory # 9781785483080
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