Cotter (biochemistry, University College, Ireland) assembles the latest research on the process of apoptosis, how it is regulated, and how it can be manipulated. Each chapter is a self-contained summary of the state-of-the art in a particular area, and includes an abstract, an introduction, and detailed descriptions of biochemical processes illustrated with two-color diagrams, plus a conclusion, summary, and extensive references. Some specific topics include the Bcl-2 family proteins, caspases, mitochondria and apoptosis, oncogenes as regulators of apoptosis, and apoptosis in disease. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)
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