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Synopsis
This monograph describes the physical principles of adhesion between particles and surfaces. These principles are applied to pharmaceutical processes involved in the manufacture of solid dosage forms such as powders, granules, tablets and dry powder inhalations. To help in the understanding of these systems, physical properties of solid surfaces, and an introduction to the theory of friction is given. Techniques for measuring particle adhesion and fracture mechanical properties of powders are introduced, as far as these are relevant to the processes discussed. The philosophy of the book deviates from that of standard pharmaceutical textbooks, in that it focuses primarily on physical principles involved in the manufacture of dosage forms rather than describing these processes purely by observation.
"synopsis" may belong to another edition of this title.
- PublisherImperial College Press
- Publication date1998
- ISBN 10 1860941125
- ISBN 13 9781860941122
- BindingHardcover
- LanguageEnglish
- Edition number1
- Number of pages256
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
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Condition: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions. Seller Inventory # Z1-N-008-00533
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
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Condition: Fair. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings. In fair condition, suitable as a study copy. Dust jacket in good condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,600grams, ISBN:9781860941122. Seller Inventory # 8988203
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
Published by
Imperial College Press, 1998
ISBN 10: 1860941125
ISBN 13: 9781860941122
Used
Hardcover
First Edition
Seller: killarneybooks, Inagh, CLARE, Ireland
Seller rating 5 out of 5 stars
Hardcover. Condition: Good. Dust Jacket Condition: Good. 1st Edition. Hardcover, ix+243 pages, NOT ex-library. Missing front blank endpaper. Pastedowns and rear blank endpaper show uneven age-tanning, text pages are clean and bright throughout with unmarked text, free of inscriptions and stamps, firmly bound. A security sticker inside the rear board. Untorn dust jacket with faint shelfworn marks, fine scratches. -- The book describes the physical principles of adhesion between particles and surfaces. These principles are applied to pharmaceutical processes involved in the manufacture of solid dosage forms such as powders, granules, tablets and dry powder inhalations. To help in the understanding of these systems, physical properties of solid surfaces, and an introduction to the theory of friction is given. Techniques for measuring particle adhesion and fracture mechanical properties of powders are introduced, as far as these are relevant to the processes discussed. -- Contents: 1 Fundamentals of Adhesion of Particles to Surfaces [Forces Causing Adhesion of Particles to Particles or Surfaces (Lifshitz-van der Waals; Capillary; Electrical; Electrostatic Image; Relation Between Lifshitz-van der Waals, Capillary, Electrical & Electrostatic Image Forces); Factors Influencing Adhesion (Surface Roughness; Work of Adhesion & Surface Free Energy; Hardness & Elasticity of Materials & Influence of Plastic, Elastic & Viscoelastic Deformation of the Materials on Adhesion; Particle Size & Shape); Models to Describe the Adhesion Force & Contact Area Between a Particle & Surface (Adhesion Model Described by Krupp & by Dahneke 1972; Johnson-Kendall-Roberts Model JKR; Deryaguin-Müller-Toporov Model DMT; JKR-Extension Described by Maugis and Barquins & by Maugis and Pollock & by Hiestand); Experimental Determination of the True Area of Contact Between Contiguous Bodies; Impaction of Particles on Plates in an Air Stream; Re-Suspension of Particles in an Air Stream]; 2 Brief Overview of the Theory of Friction [Definition & Importance of Friction Forces; Influence of the True Area of Contact on the Friction Force; Type & Strength of Bonds Between Surfaces in Relation to the Friction Force; Shear & Rupture Properties of the Interface; Tabor's Model of Friction Forces; Relationship Between Friction & Several Physical Properties of Materials; Special Features of Particle Friction]; 3 Particle Adhesion in Powder Assemblies [Powder Bulk Properties (Introduction to Powder Bulk Properties & Powder Mixing; Powder Flow; Powder Mixing); Dry Powder Inhalations (Formulation Principles for Dry Powder Aerosols; Re-Suspension of Dry Powder Inhalations); Agglomeration (Forces Between Particles in Agglomerates Prepared by Different Granulation Techniques; Mechanical Strength of Agglomerates; Analytical Expression of Agglomerate Strength; Estimation of the Fracture Stress of Spherical Agglomerates; Assessment of Agglomerate Strength from Bulk Properties); Tabletting (Adhesion Between Particles in Compacts & its Relationship to the Mechanical Strength of the Compacts; Kendall's Fracture Mechanics Approach; Empirical Relationships Between Compact Strength & Tablet & Material Properties)]; 4 Measuring Methods [Overview of the Methods to Measure Adhesion & Friction Forces Between Single Particles & Surfaces (Controlled Reduction of Adhesion Forces; Centrifuge & Aerodynamic & Hydrodynamic Technique; Impact-Separation Method; Ultrasonic Vibration; Electrical Field Detachment Technique; Miscellaneous Detachment Force Measurement Methods; Force Microscopy; Measurement Techniques to Determine Friction Forces Between Single Particles); Experimental Determination of the Young's Modulus of Elasticity (Bending; Compression; Indentation; Empirical Relationships to Extrapolate a Young's Modulus at Zero Porosity From Data Obtained on Porous Specimens); Critical Stress Intensity Factor & Related Physical Properties (Beam Bending; Radially-Edge-Cracked Discs; Indentation); Tensile Strength of Specimens (Bending; Diametral Compression)]; Bibliography. Seller Inventory # 005043
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
Seller: Books Puddle, New York, NY, U.S.A.
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Condition: New. 1st edition NO-PA29JULT2014-KAP. Seller Inventory # 26129019303
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
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Particle-Particle Adhesion in Pharmaceutical Powder Handling
Published by
World Scientific Publishing Company, 1999
ISBN 10: 1860941125
ISBN 13: 9781860941122
New
Hardcover
Seller: dsmbooks, Liverpool, United Kingdom
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Hardcover. Condition: New. New. book. Seller Inventory # D8S0-3-M-1860941125-5
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