MODIFIED CYCLODEXTRINS: SCAFFOLDS AND TEMPLATES FOR SUPRAMOLECULAR CHEMISTRY - Hardcover

Easton, Chris J; Lincoln, Stephen F

Hardcover

ISBN 10: 1860941443 ISBN 13: 9781860941443

Publisher: Imperial College Press, 1999

Synopsis

Through modification, the natural cyclodextrins are effective templates for the generation of a wide range of molecular hosts. This makes it possible to tailor a cyclodextrin host to a particular guest, to meet specific requirements in the host-guest complex, and opens the way to diverse new areas of supramolecular chemistry. Metallocyclodextrins, rotaxanes and catenanes, as well as surface monolayers of modified cyclodextrins, are readily obtained. The native cyclodextrins serve as scaffolds on which functional groups and other substituents can be assembled, with controlled geometry. This results in substantially improved molecular recognition and procedures for chemical separation, including enantiomer discrimination, through guest binding. Access to the gamut of functional groups greatly expands the utility of cyclodextrins in chemical synthesis and provides catalysts which mimic the entire range of enzymic activity. Modifications to the cyclodextrins also lead to a wide range of photochemistry of cyclodextrin complexes, through which the enhancement of guest reactivity occurs; in addition, light harvesting molecular devices and photochemical frequency switches may be constructed. In solution, modified cyclodextrins have been used to construct molecular reactors, as well as molecular, temperature and pH sensors. At surfaces, they form semipermeable membranes and sensor electrodes. Such exciting fields of chemistry, made possible only through modifications to the natural cyclodextrins, are the subject of this book.

About this title

Review

"Clearly classified, serves as a solid basis for the coming decades for all who will work on synthetic supramolecular chemistry." -- Cyclodextrin

Edition details

• Publisher: Imperial College Press
• Publication date: 1999
• ISBN 10: 1860941443
• ISBN 13: 9781860941443
• Binding: Hardcover
• Language: English
• Number of pages: 304