This second edition now includes practical information on drug enhancement of nuclear medicine studies; radiopharmaceuticals as therapeutic agents; pharmacokinetics and a section on current radiopharmaceutical research.This book begins with the basic scientific principles of radiation physics, generator systems and preparation of radiopharmaceuticals. It deals with methods of localization of radiopharmaceuticals such as lung deposition, ion exchange, membrane transportation, phagocytosis and pinocytosis. The important role of radiolabelling blood components is reviewed. The latest information on factors affecting biodistribution, adverse and unusual reactions, the integrity of radiopharmaceuticals and dosimetry is also included. There is also a section on new radiopharmaceuticals. The final chapter on paediatric radiopharmacy deals with the preparation of doses for children, methods of calculating doses and documentation.
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Recent European legislation assigning to the hospital pharmacist responsibility for the safety and efficacy of any substance prepared for administration to humans for medicinal purposes has brought forth specialized training in quality control procedures connected with radiopharmaceuticals. Coverage in this text includes basic principles of radionuclide physics; details of radiopharmaceutical dispensing, handling, documentation, labelling, packaging, and transport; factors affecting biodistribution and integrity; adverse reactions; clinical uses; dosimetric aspects; and pediatric radiopharmacy. Annotation copyright Book News, Inc. Portland, Or.
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