Fast Facts: Comprehensive Genomic Profiling - Softcover

Rapoport, Bernardo L.; Troncone, Giancarlo; Schmitt, Fernando; Nayler, Simon

 
9783318068184: Fast Facts: Comprehensive Genomic Profiling
Softcover
ISBN 10: 3318068187 ISBN 13: 9783318068184
Publisher: S Karger Ag, 2020

Synopsis

Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge or memory of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: Genetic mutations and biomarkers Understanding next-generation sequencing Elements of comprehensive genomic profiles Role in precision oncology Predictive and prognostic biomarkers Overcoming barriers to genotype-directed therapy

"synopsis" may belong to another edition of this title.

Publisher
S Karger Ag
Publication date
2020
Language
English
ISBN 10 
3318068187
ISBN 13 
9783318068184
Binding
Paperback
Edition number
1
Number of pages
108