Handbook of Chemical Glycosylation: Advances in Stereoselectivity and Therapeutic Relevance - Hardcover

Hardcover

ISBN 10: 3527317805 ISBN 13: 9783527317806

Publisher: Vch Verlagsgesellschaft Mbh, 2008

Synopsis

Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need. Covering the chemistry necessary to synthesize exact copies of these structures, top authors from all around the world comprehensively deal with synthesis from anomeric halides, from miscellaneous glycosyl donors, and by indirect and special methods, as well as 1-oxygen-and 1-sulfur-substituted derivatives. They demonstrate the best approach for the stereoselective formation of the intermonomeric bond, making this essential reading for every biochemist working in biosynthesis, the exploration of biopathways and vaccines.

About this title

About the Author:

Born in 1965, Alexei Demchenko gained his MSc in chemical engineering from Mendeleev University of Chemical Technology, Russia, in 1988, before joining the Zelinski Institute of Organic Chemistry, at the Russian Academy of Sciences, Moscow. It was here, under Professor Kochetkov, that he took his first steps in researching carbohydrate synthesis. In 1993 he was awarded a PhD for his work on the development of thiocyanate methodology for stereospecific glycosylation and, after two post-doctoral years under Kochetkov, he joined Geert-Jan Boons' group at the University of Birmingham, UK, as a BBSRC post-doctoral research fellow. In 1998 he moved with Professor Boons to the Complex Carbohydrate Research Center at the University of Georgia as a research associate, where his research focused on the synthesis of complex oligosaccharides for immunological studies and the exploration of chemical O-sialylation. In 2001 he joined the University of Missouri St. Louis as an assistant professor of chemistry and biochemistry. Professor Demchenko is a recipient of the CAREER award from the National Science Foundation, and has co-authored over 50 articles, reviews, and book chapters. His current research interests are in the field of synthetic carbohydrate chemistry.

Review:

I recommend this monograph to all those who deal with carbohydrate chemistry or wish to do so. (Angewandte Chemie, July 7, 2008)

"An excellent compilation of chemical glycosylation methods...I read this book with great pleasure...I recommend this monograph to all those who deal with carbohydrate chemistry..." (Angewandte Chemie, 29/2008)

About this edition

• Publisher: Vch Verlagsgesellschaft Mbh
• Publication date: 2008
• ISBN 10: 3527317805
• ISBN 13: 9783527317806
• Binding: Hardcover
• Edition number: 1
• Number of pages: 501
• Editor: Demchenko Alexei V.