Self Eroding Matrix System: A Self Eroding Lipid Based Matrix for an Insoluble Drug - Softcover

Dave, Vivek; Karole, Sarita; Bajaj, Jitendra

Softcover

ISBN 10: 3639348087 ISBN 13: 9783639348088

Publisher: VDM Verlag Dr. Müller, 2011

Synopsis

The aim of this study was to develop a lipid based formulation for a poorly soluble drug belonging to BCS Class II. The intention of the formulation design was to develop a ?self eroding matrix system? made of lipidic excipients which would release the drug mainly by the mechanism of erosion. To attain such as system, lipidic excipients like stearic acid and hydrogenated castor oil were used as matrix formers and surfactants like sodium lauryl sulphate and gelucire 44/14 were used as matrix modifiers. The formulations prepared were subjected to physicochemical and in vitro dissolution and erosion studies.

About this title

About the Author

Vivek Dave have done M.Pharm in Pharmaceutics from Manipal College of Pharmaceutical Sciences,India. He is Pursuing PhD from Banasthali University, Jaipur, India. His research interest in delivery of various drugs through Transdermal, Nanoparticle & Ocular route.

Edition details

• Publisher: VDM Verlag Dr. Müller
• Publication date: 2011
• Language: English
• ISBN 10: 3639348087
• ISBN 13: 9783639348088
• Binding: Paperback
• Number of pages: 120