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Influence of process parameters on various CHO fermentations: performed at the Institute of Biotechnology of the University of Natural Resources and Life Sciences in Vienna - Softcover

 
9783639391312: Influence of process parameters on various CHO fermentations: performed at the Institute of Biotechnology of the University of Natural Resources and Life Sciences in Vienna

Synopsis

Fermentations of mammalian cells play an important role in biopharmaceutical industry. Over the years yields derived from batch and fed batch cultivation increased dramatically. However, the market of biopharmaceuticals is constantly growing and many of the products require continuous application for long time periods. In order to fill the market demands, consequent improvements in clone development and bioprocess engineering are necessary. One of the most widely used expression system for production of recombinant proteins is the Chinese hamster ovary (CHO) cell line. In this work we compare growth and metabolism of two dhfr- CHO cell lines derived from two main lineages of spontaneously immortalized cell line established in 1956 (Puck) by dissection on Chinese hamster and test several approaches for bioprocess improvement, including media development.

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About the Author

Urszula Puc obtained Diplom-Ingenieur title in Biotechnology at the University of Natural Ressources and Life Sciences in Vienna. After finishing the master study she became PhD student in Renate Kunert's group.

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  • PublisherAV Akademikerverlag
  • Publication date2012
  • ISBN 10 3639391314
  • ISBN 13 9783639391312
  • BindingPaperback
  • LanguageEnglish
  • Number of pages104

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Urszula Puc
Published by AV Akademikerverlag Apr 2012, 2012
ISBN 10: 3639391314 ISBN 13: 9783639391312
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fermentations of mammalian cells play an important role in biopharmaceutical industry. Over the years yields derived from batch and fed batch cultivation increased dramatically. However, the market of biopharmaceuticals is constantly growing and many of the products require continuous application for long time periods. In order to fill the market demands, consequent improvements in clone development and bioprocess engineering are necessary. One of the most widely used expression system for production of recombinant proteins is the Chinese hamster ovary (CHO) cell line. In this work we compare growth and metabolism of two dhfr- CHO cell lines derived from two main lineages of spontaneously immortalized cell line established in 1956 (Puck) by dissection on Chinese hamster and test several approaches for bioprocess improvement, including media development. 104 pp. Englisch. Seller Inventory # 9783639391312

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Urszula Puc
Published by AV Akademikerverlag, 2012
ISBN 10: 3639391314 ISBN 13: 9783639391312
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Fermentations of mammalian cells play an important role in biopharmaceutical industry. Over the years yields derived from batch and fed batch cultivation increased dramatically. However, the market of biopharmaceuticals is constantly growing and many of the products require continuous application for long time periods. In order to fill the market demands, consequent improvements in clone development and bioprocess engineering are necessary. One of the most widely used expression system for production of recombinant proteins is the Chinese hamster ovary (CHO) cell line. In this work we compare growth and metabolism of two dhfr- CHO cell lines derived from two main lineages of spontaneously immortalized cell line established in 1956 (Puck) by dissection on Chinese hamster and test several approaches for bioprocess improvement, including media development. Seller Inventory # 9783639391312

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Urszula Puc|Renate Kunert|Christian Leitner
Published by AV Akademikerverlag, 2012
ISBN 10: 3639391314 ISBN 13: 9783639391312
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Puc UrszulaUrszula Puc obtained Diplom-Ingenieur title in Biotechnology at the University of Natural Ressources and Life Sciences in Vienna. After finishing the master study she became PhD student in Renate Kunert s group.Ferment. Seller Inventory # 4983366

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