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Synopsis
In recent decades, the tremendous biological potential of the highly substituted pyrazole scaffolds have attracted many chemists to synthesize this class of molecules. The classical methods to synthesized pyrazoles and involves the condensation of diketone compound or its synthetic equivalent with hydrazine in appropriate organic solvent. On the other hand, functionalized ketene dithioacetals are versatile intermediates in organic synthesis for the construction of substituted heterocycles such as pyrazoles. Thus, the practical synthesis of poly substituted pyrazole based small molecules is of great importance. The present research has demonstrated the synthesis of highly functionalized Pyrazoles using ketene dithioacetal and followed by N-alkylation using TBAB and water as solvent in excellent yield and its biological study.
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Synthesis of Highly Functionalized Pyrazoles Using Ketene Dithioacetal
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Synthesis of Highly Functionalized Pyrazoles Using Ketene Dithioacetal
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Synthesis of Highly Functionalized Pyrazoles Using Ketene Dithioacetal
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Savant MaheshIs working as Asst. Prof. at Dept. of Industrial Chemistry at Shree M. & N. Virani Science College, Rajkot since 2012. He obtained his Ph.D. degree from Dept. of Chemistry, Saurashtra University, Rajkot, India. He did po. Seller Inventory # 561658570
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