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Engineering of Halogenases towards Synthetic Applications: Increasing the Thermostability and Investigations on a Marine Brominase Bmp5 (BestMasters) - Softcover
Synopsis
Hannah Minges focuses on the investigation of two different FAD-dependent halogenases in order to analyze and improve their applicability for chemoenzymatic approaches in chemistry. Owing to beneficial features, like high selectivity and benign reaction conditions, nature’s toolkit for halogenation provides several advantages, whereas conventional chemical strategies require hazardous reagents and suffer from low selectivity. Therefore, enzymatic halogenation arises as promising alternative in the synthesis of valuable chemicals. One project focuses on the generation of a thermostable variant of the tryptophan halogenase Thal by means of directed evolution. The second project deals with the investigation of the marine halogenase Bmp5. This enzyme is of synthetic interest because it preferably introduces bromine into phenol compounds, whereas chlorination cannot take place.
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About the Author
Hannah Minges, a Ph.D student at Bielefeld University, works on the optimization of tryptophan halogenases by means of directed evolution.
"About this title" may belong to another edition of this title.
- PublisherSpringer Spektrum
- Publication date2017
- ISBN 10 3658184094
- ISBN 13 9783658184094
- BindingPaperback
- LanguageEnglish
- Edition number1
- Number of pages128
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Engineering of Halogenases towards Synthetic Applications
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Hannah Minges focuses on the investigation of two different FAD-dependent halogenases in order to analyze and improve their applicability for chemoenzymatic approaches in chemistry. Owing to beneficial features, like high selectivity and benign reaction conditions, nature's toolkit for halogenation provides several advantages, whereas conventional chemical strategies require hazardous reagents and suffer from low selectivity. Therefore, enzymatic halogenation arises as promising alternative in the synthesis of valuable chemicals. One project focuses on the generation of a thermostable variant of the tryptophan halogenase Thal by means of directed evolution. The second project deals with the investigation of the marine halogenase Bmp5. This enzyme is of synthetic interest because it preferably introduces bromine into phenol compounds, whereas chlorination cannot take place. 116 pp. Englisch. Seller Inventory # 9783658184094
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Engineering of Halogenases towards Synthetic Applications: Increasing the Thermostability and Investigations on a Marine Brominase Bmp5 (BestMasters)
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Engineering of Halogenases towards Synthetic Applications : Increasing the Thermostability and Investigations on a Marine Brominase Bmp5
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Engineering of Halogenases towards Synthetic Applications : Increasing the Thermostability and Investigations on a Marine Brominase Bmp5
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Hannah Minges focuses on the investigation of two different FAD-dependent halogenases in order to analyze and improve their applicability for chemoenzymatic approaches in chemistry. Owing to beneficial features, like high selectivity and benign reaction conditions, nature's toolkit for halogenation provides several advantages, whereas conventional chemical strategies require hazardous reagents and suffer from low selectivity. Therefore, enzymatic halogenation arises as promising alternative in the synthesis of valuable chemicals. One project focuses on the generation of a thermostable variant of the tryptophan halogenase Thal by means of directed evolution. The second project deals with the investigation of the marine halogenase Bmp5. This enzyme is of synthetic interest because it preferably introduces bromine into phenol compounds, whereas chlorination cannot take place. Seller Inventory # 9783658184094
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Engineering of Halogenases towards Synthetic Applications: Increasing the Thermostability and Investigations on a Marine Brominase Bmp5 (BestMasters)
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Engineering of Halogenases Towards Synthetic Applications: Increasing the Thermostability and Investigations on a Marine Brominase Bmp5
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Engineering of Halogenases towards Synthetic Applications: Increasing the Thermostability and Investigations on a Marine Brominase Bmp5 (BestMasters)
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