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Historically, oral drug administration has been the predominant route for drug delivery. Over the past three decades, the pursuit and exploration of devices designed to be retained in the upper part of the gastrointestinal (GI) tract has advanced consistently in terms of technology and diversity, encompassing a variety of systems and devices such as floating systems, raft systems, expanding systems, swelling systems, bioadhesive systems and low-density systems. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region. Also, longer residence time in the stomach could be advantageous for local action in the upper part of the small intestine, for example treatment of peptic ulcer disease. Furthermore, improved bioavailability is expected for drugs that are absorbed readily upon release in the GI tract. These drugs can be delivered ideally by slow release from the stomach. Many drugs categorised as once-a-day delivery have been demonstrated to have suboptimal absorption due to dependence on the transit time of the dosage form, These drugs can be delivered ideally by slow release from the stomach.
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He is currently a PhD scholar (Pharmaceutics) and doing research work in Department of Pharmacy in Vikarm University, Ujjain (India) and taught Pharmaceutics, Pharma-tech, Bio-pharmaceutics. Previously, he has worked in pharmaceutical industry in production department. He has published several research & review articles in various renowned journals
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- PublisherLAP LAMBERT Academic Publishing
- Publication date2012
- ISBN 10 3659120383
- ISBN 13 9783659120381
- BindingPaperback
- Number of pages68
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Gastroretentive Dosage Forms: Floating Tablets
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Historically, oral drug administration has been the predominant route for drug delivery. Over the past three decades, the pursuit and exploration of devices designed to be retained in the upper part of the gastrointestinal (GI) tract has advanced consistently in terms of technology and diversity, encompassing a variety of systems and devices such as floating systems, raft systems, expanding systems, swelling systems, bioadhesive systems and low-density systems. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region. Also, longer residence time in the stomach could be advantageous for local action in the upper part of the small intestine, for example treatment of peptic ulcer disease. Furthermore, improved bioavailability is expected for drugs that are absorbed readily upon release in the GI tract. These drugs can be delivered ideally by slow release from the stomach. Many drugs categorised as once-a-day delivery have been demonstrated to have suboptimal absorption due to dependence on the transit time of the dosage form, These drugs can be delivered ideally by slow release from the stomach. 68 pp. Englisch. Seller Inventory # 9783659120381
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Gastroretentive Dosage Forms Floating Tablets
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Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Historically, oral drug administration has been the predominant route for drug delivery. Over the past three decades, the pursuit and exploration of devices designed to be retained in the upper part of the gastrointestinal (GI) tract has advanced consistently in terms of technology and diversity, encompassing a variety of systems and devices such as floating systems, raft systems, expanding systems, swelling systems, bioadhesive systems and low-density systems. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region. Also, longer residence time in the stomach could be advantageous for local action in the upper part of the small intestine, for example treatment of peptic ulcer disease. Furthermore, improved bioavailability is expected for drugs that are absorbed readily upon release in the GI tract. These drugs can be delivered ideally by slow release from the stomach. Many drugs categorised as once-a-day delivery have been demonstrated to have suboptimal absorption due to dependence on the transit time of the dosage form, These drugs can be delivered ideally by slow release from the stomach. Seller Inventory # 9783659120381
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Book Description Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Khirwadkar PraveenHe is currently a PhD scholar (Pharmaceutics) and doing research work in Department of Pharmacy in Vikarm University, Ujjain (India) and taught Pharmaceutics, Pharma-tech, Bio-pharmaceutics. Previously, he has worke. Seller Inventory # 5132795
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