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Potential HIV Reverse Transcriptase Inhibitors: Synthesis of Benzyloxy Substituted 4,6- Diarylpyrimidine as potential HIV Reverse Transcriptase Inhibitors - Softcover
The existence of CNS viral reservoirs is the main cause of recurrence of HIV infection after medication is withdrawn. This problem remains unsolved because of poor CNS penetration with the existing anti retroviral drugs. To meet the demand of crossing the blood-brain barrier (BBB) the compound should have polar surface area (PSA). PSA is defined as the surface area occupied by oxygen and nitrogen atoms and hydrogen atoms attached to these atoms. With this aspect in view, we calculated the PSA values of various substituent on the aryl rings in our aimed compounds and they were found within the prescribed limits so we proceeded with the synthesis of the compounds.
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About the Author:
Ms. Komal Patel has obtained her Master of Pharmacy degree in Pharmaceutical Chemistry in 2010. She has published different international and National Research paper in synthetic Chemistry, Analytical Chemistry and Drug Design.
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- PublisherLAP LAMBERT Academic Publishing
- Publication date2012
- ISBN 10 3659184713
- ISBN 13 9783659184710
- BindingPaperback
- Number of pages68
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Potential HIV Reverse Transcriptase Inhibitors: Synthesis of Benzyloxy Substituted 4,6- Diarylpyrimidine as potential HIV Reverse Transcriptase Inhibitors
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Potential HIV Reverse Transcriptase Inhibitors
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Potential HIV Reverse Transcriptase Inhibitors Synthesis of Benzyloxy Substituted 4,6 Diarylpyrimidine as potential HIV Reverse Transcriptase Inhibitors
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The existence of CNS viral reservoirs is the main cause of recurrence of HIV infection after medication is withdrawn. This problem remains unsolved because of poor CNS penetration with the existing anti retroviral drugs. To meet the demand of crossing the blood-brain barrier (BBB) the compound should have polar surface area (PSA). PSA is defined as the surface area occupied by oxygen and nitrogen atoms and hydrogen atoms attached to these atoms. With this aspect in view, we calculated the PSA values of various substituent on the aryl rings in our aimed compounds and they were found within the prescribed limits so we proceeded with the synthesis of the compounds. 68 pp. Englisch. Seller Inventory # 9783659184710
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Potential HIV Reverse Transcriptase Inhibitors : Synthesis of Benzyloxy Substituted 4,6- Diarylpyrimidine as potential HIV Reverse Transcriptase Inhibitors
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Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The existence of CNS viral reservoirs is the main cause of recurrence of HIV infection after medication is withdrawn. This problem remains unsolved because of poor CNS penetration with the existing anti retroviral drugs. To meet the demand of crossing the blood-brain barrier (BBB) the compound should have polar surface area (PSA). PSA is defined as the surface area occupied by oxygen and nitrogen atoms and hydrogen atoms attached to these atoms. With this aspect in view, we calculated the PSA values of various substituent on the aryl rings in our aimed compounds and they were found within the prescribed limits so we proceeded with the synthesis of the compounds. Seller Inventory # 9783659184710
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Potential HIV Reverse Transcriptase Inhibitors Synthesis of Benzyloxy Substituted 4,6 Diarylpyrimidine as potential HIV Reverse Transcriptase Inhibitors
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Potential HIV Reverse Transcriptase Inhibitors
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Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: P. Patel KomalMs. Komal Patel has obtained her Master of Pharmacy degree in Pharmaceutical Chemistry in 2010. She has published different international and National Research paper in synthetic Chemistry, Analytical Chemistry and Drug. Seller Inventory # 5137842
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