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Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride: For Improved Efficacy Using Disintegrant Blends - Softcover
Synopsis
Recent advances in novel drug delivery system aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach is fast dissolving tablets (FDT) of Phenylephrine Hydrochloride, a selective α1 adrenergic receptor antagonist, used for nasal decongestant and producing mydriasis effect. In present work an attempt has been made by formulating fast dissolving tablets of Phenylephrine Hydrochloride by superdisintegrants addition method using croscarmellose sodium, crospovidone and sodium starch glycolate. A total of 10 batches were prepared by using various combination and concentration of superdisintegrants and evaluated for general appearance and physical parameters, drug content, in vitro disintegration, in vitro dispersion, in vitro drug release studies, kinetic studies and stability studies. Amongst all the formulations F2 and F9 were found to be better formulations which include single superdisintegrants and combination of superdisintegrants. Finally it was concluded that FDT of Phenylephrine Hydrochloride will be used as a novel drug dosage form for pediatrics and geriatrics.
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About the Author
Nikunj Chapla, completed Master of Pharmacy, Pharmaceutics from Department of Pharmaceutics, Nitte Gulabi Shetty Memorial Institute of Pharmaceutical Sciences Deralakatte, Mangalore at NITTE University.
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Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride
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LAP Lambert Academic Publishing Dez 2016, 2016
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ISBN 13: 9783659346040
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent advances in novel drug delivery system aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach is fast dissolving tablets (FDT) of Phenylephrine Hydrochloride, a selective 1 adrenergic receptor antagonist, used for nasal decongestant and producing mydriasis effect. In present work an attempt has been made by formulating fast dissolving tablets of Phenylephrine Hydrochloride by superdisintegrants addition method using croscarmellose sodium, crospovidone and sodium starch glycolate. A total of 10 batches were prepared by using various combination and concentration of superdisintegrants and evaluated for general appearance and physical parameters, drug content, in vitro disintegration, in vitro dispersion, in vitro drug release studies, kinetic studies and stability studies. Amongst all the formulations F2 and F9 were found to be better formulations which include single superdisintegrants and combination of superdisintegrants. Finally it was concluded that FDT of Phenylephrine Hydrochloride will be used as a novel drug dosage form for pediatrics and geriatrics. 148 pp. Englisch. Seller Inventory # 9783659346040
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Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride : For Improved Efficacy Using Disintegrant Blends
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ISBN 10: 3659346047
ISBN 13: 9783659346040
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Recent advances in novel drug delivery system aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach is fast dissolving tablets (FDT) of Phenylephrine Hydrochloride, a selective 1 adrenergic receptor antagonist, used for nasal decongestant and producing mydriasis effect. In present work an attempt has been made by formulating fast dissolving tablets of Phenylephrine Hydrochloride by superdisintegrants addition method using croscarmellose sodium, crospovidone and sodium starch glycolate. A total of 10 batches were prepared by using various combination and concentration of superdisintegrants and evaluated for general appearance and physical parameters, drug content, in vitro disintegration, in vitro dispersion, in vitro drug release studies, kinetic studies and stability studies. Amongst all the formulations F2 and F9 were found to be better formulations which include single superdisintegrants and combination of superdisintegrants. Finally it was concluded that FDT of Phenylephrine Hydrochloride will be used as a novel drug dosage form for pediatrics and geriatrics. Seller Inventory # 9783659346040
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Formulation of Fast Dissolving Tablets of Phenylephrine Hydrochloride
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Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Chapla NikunjNikunj Chapla, completed Master of Pharmacy, Pharmaceutics from Department of Pharmaceutics, Nitte Gulabi Shetty Memorial Institute of Pharmaceutical Sciences Deralakatte, Mangalore at NITTE University.Recent advance. Seller Inventory # 5150054
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Formulation of Fast Dissolving Tablets of Phenylephrine Hydrochloride
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2013
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Formulation of Fast Dissolving Tablets of Phenylephrine Hydrochloride
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Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride: For Improved Efficacy Using Disintegrant Blends
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Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Recent advances in novel drug delivery system aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach is fast dissolving tablets (FDT) of Phenylephrine Hydrochloride, a selective ¿1 adrenergic receptor antagonist, used for nasal decongestant and producing mydriasis effect. In present work an attempt has been made by formulating fast dissolving tablets of Phenylephrine Hydrochloride by superdisintegrants addition method using croscarmellose sodium, crospovidone and sodium starch glycolate. A total of 10 batches were prepared by using various combination and concentration of superdisintegrants and evaluated for general appearance and physical parameters, drug content, in vitro disintegration, in vitro dispersion, in vitro drug release studies, kinetic studies and stability studies. Amongst all the formulations F2 and F9 were found to be better formulations which include single superdisintegrants and combination of superdisintegrants. Finally it was concluded that FDT of Phenylephrine Hydrochloride will be used as a novel drug dosage form for pediatrics and geriatrics.OmniScriptum SRL, Str. Armeneasca 28/1, office 1, 2012 Chisinau 148 pp. Englisch. Seller Inventory # 9783659346040
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Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride | For Improved Efficacy Using Disintegrant Blends
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Taschenbuch. Condition: Neu. Formulation Of Fast Dissolving Tablets Of Phenylephrine Hydrochloride | For Improved Efficacy Using Disintegrant Blends | Nikunj Chapla (u. a.) | Taschenbuch | 148 S. | Englisch | 2016 | LAP LAMBERT Academic Publishing | EAN 9783659346040 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 106063237
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