Computational methods for screening and engineering enzyme properties

 
9783659346255: Computational methods for screening and engineering enzyme properties

Biocatalysis is an excellent alternative to classical chemical catalysis offering environmentally benign manufacturing, sustainable development and green chemistry. Understanding enzyme properties at an atomic level is the major advantage offered by computational techniques and the only route for rational engineering of enzyme properties. This work describes specifically developed state of the art methodologies that deal with enzyme reaction promiscuity and substrate promiscuity phenomena. An innovative tool for in silico enzyme evolution and screening has also been developed and its assembly from scratch and validation are thoroughly described. The existing drawbacks of industrial application of enzymes need to be overcome by a combined effort of scientists in which computational chemists and biologists have much to contribute.

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About the Author:

Dr. Lorena Knapic received her PhD form University of Trieste (Italy) in 2012. Her research was conducted in the laboratory of computational and applied biocatalysis led by prof. Lucia Gardossi. With studies done in Croatia, Italy, Sweden and Taiwan, she always aims at combining scientific excellence with a thrilling lifestyle.

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Book Description LAP Lambert Academic Publishing, United States, 2013. Paperback. Book Condition: New. 220 x 150 mm. Language: English . Brand New Book ***** Print on Demand *****.Biocatalysis is an excellent alternative to classical chemical catalysis offering environmentally benign manufacturing, sustainable development and green chemistry. Understanding enzyme properties at an atomic level is the major advantage offered by computational techniques and the only route for rational engineering of enzyme properties. This work describes specifically developed state of the art methodologies that deal with enzyme reaction promiscuity and substrate promiscuity phenomena. An innovative tool for in silico enzyme evolution and screening has also been developed and its assembly from scratch and validation are thoroughly described. The existing drawbacks of industrial application of enzymes need to be overcome by a combined effort of scientists in which computational chemists and biologists have much to contribute. Bookseller Inventory # AAV9783659346255

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Book Description LAP LAMBERT Academic Publishing. Paperback. Book Condition: New. Paperback. 180 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.Biocatalysis is an excellent alternative to classical chemical catalysis offering environmentally benign manufacturing, sustainable development and green chemistry. Understanding enzyme properties at an atomic level is the major advantage offered by computational techniques and the only route for rational engineering of enzyme properties. This work describes specifically developed state of the art methodologies that deal with enzyme reaction promiscuity and substrate promiscuity phenomena. An innovative tool for in silico enzyme evolution and screening has also been developed and its assembly from scratch and validation are thoroughly described. The existing drawbacks of industrial application of enzymes need to be overcome by a combined effort of scientists in which computational chemists and biologists have much to contribute. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783659346255

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