Method development for analysis of Amphetamine-type drugs using GC-MS: Forensic Toxicology & drugs Abuse - Softcover

Sharma, Mahesh

Softcover

ISBN 10: 365945267X ISBN 13: 9783659452673

Publisher: LAP LAMBERT Academic Publishing, 2013

Synopsis

Forensic toxicology is the application of toxicology to the matter of law. This work is based on forensic drug testing field of forensic toxicology. Nowadays, the abusing of drugs is considered as a very intense problem which occurring in communities. More and more people are getting addicted to drugs and many are the drug dealers. The main purpose of the present study was the drug profiling and identification of eight Amphetamine-type stimulants (d-amphetamine sulphate, (+)-methamphetamine, Ibuprofen, Piperazine hexahydrate, 1-(4-methoxyphenyl) piperazine, 1-(4-trifluoromethylphenyl) piperazine, 1-Benzylpiperazine and 1-(2-methoxyphenyl) piperazine) by developing a GC-MS method which would detect all the above drugs at the same time. Quinoline was used as internal standard (IS) during the present GC-MS analysis. The first step was the individual drug analysis by the developed GC-MS method and the next step was the mixed drug analysis. The drugs were derivatised by the acylation reagent PFPA, however the silylation reagent BSTFA:TMCS (99:1) was also used as an alternative to acylation. The standard curve of each drug was plotted and the LOD & LOQ was calculated.

About this title

About the Author

Forensic Expert & Investigator at SIFS INDIA, Fellow International Science Congress Association,Fellow-SIFS INDIA,M.Sc. in Forensic Science (Cambridge, UK), M.Sc. in Bioinformatics (Delhi,India),Microbiologist + Pharmacist (DAVV-Indore, India)

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2013
• Language: English
• ISBN 10: 365945267X
• ISBN 13: 9783659452673
• Binding: Paperback
• Number of pages: 108