Development and Evaluation of Fast Dissolving Tablet of Loratadine: Using Solid Dispersion Technique - Softcover
Synopsis
Loratadine is a non sedative anti-histaminic drug. Its major use is in control of congestion, sneezing, runny nose and itching that a patient suffers with an allergic attack or an infection. It has poor solubility in water. Therefore, the solubility and drug release were enhanced using the solid dispersion technique and fast dissolving tablet were formulated. Solid dispersion prepared using Poloxamer 407, PEG 6000 and urea. The solid dispersion were evaluated for saturation solubility, drug content and in vitro dissolution study and it was characterized using FT-IR, X-RD, SEM and DSC study. The fast dissolving tablets of loratadine was formulated using crospovidone and crosscarmelose sodium by direct compression method. The tablets were evaluated for thickness, hardness, weight variation, friability, disintegration time and % in vitro drug release. A 32 factorial design was used to study the effect of Loratadine: Poloxamer 407 and crospovidone on disintegration time and % in vitro drug release. The responses were analyzed using ANOVA. The obtained model was validated & optimized formulation was prepared as suggested by the software.
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About the Author
Nidhi Sherathiya, Master of Pharmacy, Pharmaceuticsat Gujarat Technological University, Pharmacy Scholar at S. J. Thakkar Pharmacy College, Rajkot, Gujarat, India.
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Development and Evaluation of Fast Dissolving Tablet of Loratadine
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LAP LAMBERT Academic Publishing Okt 2013, 2013
ISBN 10: 3659479780
ISBN 13: 9783659479786
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Loratadine is a non sedative anti-histaminic drug. Its major use is in control of congestion, sneezing, runny nose and itching that a patient suffers with an allergic attack or an infection. It has poor solubility in water. Therefore, the solubility and drug release were enhanced using the solid dispersion technique and fast dissolving tablet were formulated. Solid dispersion prepared using Poloxamer 407, PEG 6000 and urea. The solid dispersion were evaluated for saturation solubility, drug content and in vitro dissolution study and it was characterized using FT-IR, X-RD, SEM and DSC study. The fast dissolving tablets of loratadine was formulated using crospovidone and crosscarmelose sodium by direct compression method. The tablets were evaluated for thickness, hardness, weight variation, friability, disintegration time and % in vitro drug release. A 32 factorial design was used to study the effect of Loratadine: Poloxamer 407 and crospovidone on disintegration time and % in vitro drug release. The responses were analyzed using ANOVA. The obtained model was validated & optimized formulation was prepared as suggested by the software. 120 pp. Englisch. Seller Inventory # 9783659479786
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Development and Evaluation of Fast Dissolving Tablet of Loratadine
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Development and Evaluation of Fast Dissolving Tablet of Loratadine
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Development and Evaluation of Fast Dissolving Tablet of Loratadine
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sherathiya NidhiNidhi Sherathiya, Master of Pharmacy, Pharmaceuticsat Gujarat Technological University, Pharmacy Scholar at S. J. Thakkar Pharmacy College, Rajkot, Gujarat, India.Loratadine is a non sedative anti-histaminic drug. Seller Inventory # 5158664
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Development and Evaluation of Fast Dissolving Tablet of Loratadine
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2013
ISBN 10: 3659479780
ISBN 13: 9783659479786
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Development and Evaluation of Fast Dissolving Tablet of Loratadine
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LAP LAMBERT Academic Publishing Okt 2013, 2013
ISBN 10: 3659479780
ISBN 13: 9783659479786
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Loratadine is a non sedative anti-histaminic drug. Its major use is in control of congestion, sneezing, runny nose and itching that a patient suffers with an allergic attack or an infection. It has poor solubility in water. Therefore, the solubility and drug release were enhanced using the solid dispersion technique and fast dissolving tablet were formulated. Solid dispersion prepared using Poloxamer 407, PEG 6000 and urea. The solid dispersion were evaluated for saturation solubility, drug content and in vitro dissolution study and it was characterized using FT-IR, X-RD, SEM and DSC study. The fast dissolving tablets of loratadine was formulated using crospovidone and crosscarmelose sodium by direct compression method. The tablets were evaluated for thickness, hardness, weight variation, friability, disintegration time and % in vitro drug release. A 32 factorial design was used to study the effect of Loratadine: Poloxamer 407 and crospovidone on disintegration time and % in vitro drug release. The responses were analyzed using ANOVA. The obtained model was validated & optimized formulation was prepared as suggested by the software.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 120 pp. Englisch. Seller Inventory # 9783659479786
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Development and Evaluation of Fast Dissolving Tablet of Loratadine : Using Solid Dispersion Technique
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LAP LAMBERT Academic Publishing, 2013
ISBN 10: 3659479780
ISBN 13: 9783659479786
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Loratadine is a non sedative anti-histaminic drug. Its major use is in control of congestion, sneezing, runny nose and itching that a patient suffers with an allergic attack or an infection. It has poor solubility in water. Therefore, the solubility and drug release were enhanced using the solid dispersion technique and fast dissolving tablet were formulated. Solid dispersion prepared using Poloxamer 407, PEG 6000 and urea. The solid dispersion were evaluated for saturation solubility, drug content and in vitro dissolution study and it was characterized using FT-IR, X-RD, SEM and DSC study. The fast dissolving tablets of loratadine was formulated using crospovidone and crosscarmelose sodium by direct compression method. The tablets were evaluated for thickness, hardness, weight variation, friability, disintegration time and % in vitro drug release. A 32 factorial design was used to study the effect of Loratadine: Poloxamer 407 and crospovidone on disintegration time and % in vitro drug release. The responses were analyzed using ANOVA. The obtained model was validated & optimized formulation was prepared as suggested by the software. Seller Inventory # 9783659479786
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Development and Evaluation of Fast Dissolving Tablet of Loratadine | Using Solid Dispersion Technique
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ISBN 13: 9783659479786
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Taschenbuch. Condition: Neu. Development and Evaluation of Fast Dissolving Tablet of Loratadine | Using Solid Dispersion Technique | Nidhi Sherathiya (u. a.) | Taschenbuch | 120 S. | Englisch | 2013 | LAP LAMBERT Academic Publishing | EAN 9783659479786 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Seller Inventory # 105598818
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