Formulation Of Phenytoin Complexes For Dissolution Enhancement: Inclusion Complexation Using Β-cyclodextrin And Hp Β-cyclodextrin - Softcover
Synopsis
Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period.
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About the Author
Maulika S Patel, M. Pharmacy in Pharmaceutical Technology in Shree Krishna Institute of Pharmacy, Shankhalpur, becharaji at Gujarat Technological University, Ahmedabad, Gujarat, India.
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Formulation Of Phenytoin Complexes For Dissolution Enhancement
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LAP LAMBERT Academic Publishing Mai 2014, 2014
ISBN 10: 3659537055
ISBN 13: 9783659537059
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period. 152 pp. Englisch. Seller Inventory # 9783659537059
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Formulation Of Phenytoin Complexes For Dissolution Enhancement
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Maulika PatelMaulika S Patel, M. Pharmacy in Pharmaceutical Technology in Shree Krishna Institute of Pharmacy, Shankhalpur, becharaji at Gujarat Technological University, Ahmedabad, Gujarat, India.Phenytoin Inclusion complex prep. Seller Inventory # 5163202
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Formulation Of Phenytoin Complexes For Dissolution Enhancement
Published by
LAP LAMBERT Academic Publishing Mai 2014, 2014
ISBN 10: 3659537055
ISBN 13: 9783659537059
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period.Books on Demand GmbH, Überseering 33, 22297 Hamburg 152 pp. Englisch. Seller Inventory # 9783659537059
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Formulation Of Phenytoin Complexes For Dissolution Enhancement | Inclusion Complexation Using ¿-cyclodextrin And Hp ¿-cyclodextrin
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Taschenbuch. Condition: Neu. Formulation Of Phenytoin Complexes For Dissolution Enhancement | Inclusion Complexation Using ¿-cyclodextrin And Hp ¿-cyclodextrin | Patel Maulika (u. a.) | Taschenbuch | 152 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659537059 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Seller Inventory # 105242708
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Formulation Of Phenytoin Complexes For Dissolution Enhancement : Inclusion Complexation Using ¿-cyclodextrin And Hp ¿-cyclodextrin
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ISBN 13: 9783659537059
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period. Seller Inventory # 9783659537059
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Formulation Of Phenytoin Complexes For Dissolution Enhancement: Inclusion Complexation Using -cyclodextrin And Hp -cyclodextrin
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ISBN 13: 9783659537059
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