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How Duplications Influence Genome Defense in Neurospora: Neurospora Duplications and Genome Defense - Softcover
Synopsis
Genome defence processes such as repeat induced point mutation (RIP) and meiotic silencing were discovered in Neurospora, and are thought to be responsible for maintaining its genome free of transposable elements and other repeated DNA. Both, small gene-sized duplications, and larger (i.e., > 100 kbp) chromosome segment duplications (Dps), are substrates for RIP. Crosses heterozygous for large Dps make normal looking perithecia but produce vary few ascospores. This, “barren” phenotype is caused by meiotic silencing by unpaired DNA. This book is based on our research which characterised the breakpoint junctions of several Dp–generating translocations, showed that large Dps are suppressors of RIP, and identified the first Neurospora wild strains that suppress meiotic silencing. It gives important information on how Dps influence genome defence and how recognizing this has opened new directions for studies. The book will be useful for research laboratories working with Neurospora, and other fungi, and also for University students to understand recent trends in classical Neurospora genetics.
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- PublisherLAP LAMBERT Academic Publishing
- Publication date2018
- ISBN 10 3659550949
- ISBN 13 9783659550942
- BindingPaperback
- LanguageEnglish
- Number of pages140
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How Duplications Influence Genome Defense in Neurospora
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LAP LAMBERT Academic Publishing Jun 2018, 2018
ISBN 10: 3659550949
ISBN 13: 9783659550942
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Genome defence processes such as repeat induced point mutation (RIP) and meiotic silencing were discovered in Neurospora, and are thought to be responsible for maintaining its genome free of transposable elements and other repeated DNA. Both, small gene-sized duplications, and larger (i.e., 100 kbp) chromosome segment duplications (Dps), are substrates for RIP. Crosses heterozygous for large Dps make normal looking perithecia but produce vary few ascospores. This, 'barren' phenotype is caused by meiotic silencing by unpaired DNA. This book is based on our research which characterised the breakpoint junctions of several Dp-generating translocations, showed that large Dps are suppressors of RIP, and identified the first Neurospora wild strains that suppress meiotic silencing. It gives important information on how Dps influence genome defence and how recognizing this has opened new directions for studies. The book will be useful for research laboratories working with Neurospora, and other fungi, and also for University students to understand recent trends in classical Neurospora genetics. 140 pp. Englisch. Seller Inventory # 9783659550942
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How Duplications Influence Genome Defense in Neurospora : Neurospora Duplications and Genome Defense
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3659550949
ISBN 13: 9783659550942
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Taschenbuch
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Genome defence processes such as repeat induced point mutation (RIP) and meiotic silencing were discovered in Neurospora, and are thought to be responsible for maintaining its genome free of transposable elements and other repeated DNA. Both, small gene-sized duplications, and larger (i.e., 100 kbp) chromosome segment duplications (Dps), are substrates for RIP. Crosses heterozygous for large Dps make normal looking perithecia but produce vary few ascospores. This, 'barren' phenotype is caused by meiotic silencing by unpaired DNA. This book is based on our research which characterised the breakpoint junctions of several Dp-generating translocations, showed that large Dps are suppressors of RIP, and identified the first Neurospora wild strains that suppress meiotic silencing. It gives important information on how Dps influence genome defence and how recognizing this has opened new directions for studies. The book will be useful for research laboratories working with Neurospora, and other fungi, and also for University students to understand recent trends in classical Neurospora genetics. Seller Inventory # 9783659550942
Quantity: 1 available
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How Duplications Influence Genome Defense in Neurospora
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3659550949
ISBN 13: 9783659550942
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: K. Singh ParmitParmit K. Singh received his Ph.D. from the Centre for Cellular and Molecular Biology. Currently, he is a postdoctoral fellow at the National Institutes of Health, USA. Durgadas P. Kasbekar obtained his Ph.D. from the . Seller Inventory # 385767595
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How Duplications Influence Genome Defense in Neurospora: Neurospora Duplications and Genome Defense
Published by
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3659550949
ISBN 13: 9783659550942
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