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Synopsis
Oral cancer pathogenesis is a complex process involving genetic alteration during multistep carcinogenesis, growth regulation, apoptosis, immortalization, angiogenesis, invasion and metastasis. Molecular markers such as p53, Cyclin-D1 and EGFR regulate cell cycle and play important role in tumor progression and development. The present study evaluates the expressions of these molecular markers & its prognostic significance with treatment response in oral cancer patients undergoing chemoradiation. The strong positive expressions of p53, Cyclin-D1 and EGFR showed significantly lower survival as compared to negative or moderate positive expressions. Hence, expression of p53, Cyclin-D1 and EGFR may serve as a prognostic marker in oral cancer patients.
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- PublisherLAP Lambert Academic Publishing
- Publication date2015
- ISBN 10 3659672912
- ISBN 13 9783659672910
- BindingPaperback
- Number of pages64
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Expression of p53, Cyclin-D1 & EGFR in oral squamous cell carcinoma
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Expression of p53, Cyclin-D1 & EGFR in oral squamous cell carcinoma
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Oral cancer pathogenesis is a complex process involving genetic alteration during multistep carcinogenesis, growth regulation, apoptosis, immortalization, angiogenesis, invasion and metastasis. Molecular markers such as p53, Cyclin-D1 and EGFR regulate cell cycle and play important role in tumor progression and development. The present study evaluates the expressions of these molecular markers & its prognostic significance with treatment response in oral cancer patients undergoing chemoradiation. The strong positive expressions of p53, Cyclin-D1 and EGFR showed significantly lower survival as compared to negative or moderate positive expressions. Hence, expression of p53, Cyclin-D1 and EGFR may serve as a prognostic marker in oral cancer patients. 64 pp. Englisch. Seller Inventory # 9783659672910
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Expression of p53, Cyclin-D1 & EGFR in oral squamous cell carcinoma : Molecular Marker Expression in Oral Cancer
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Oral cancer pathogenesis is a complex process involving genetic alteration during multistep carcinogenesis, growth regulation, apoptosis, immortalization, angiogenesis, invasion and metastasis. Molecular markers such as p53, Cyclin-D1 and EGFR regulate cell cycle and play important role in tumor progression and development. The present study evaluates the expressions of these molecular markers & its prognostic significance with treatment response in oral cancer patients undergoing chemoradiation. The strong positive expressions of p53, Cyclin-D1 and EGFR showed significantly lower survival as compared to negative or moderate positive expressions. Hence, expression of p53, Cyclin-D1 and EGFR may serve as a prognostic marker in oral cancer patients. Seller Inventory # 9783659672910
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Expression of p53, Cyclin-D1 & EGFR in oral squamous cell carcinoma
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