Copper Complexes - Vol II: Synthesis, Characterization and Biological Evaluation of NNS donor schiff base molecular adducts of Copper (II) Chloride - Softcover

Kothari, Richa

Softcover

ISBN 10: 3659880574 ISBN 13: 9783659880575

Publisher: LAP LAMBERT Academic Publishing, 2016

Synopsis

NNS Schiff base molecular adducts belong to a group of thiourea derivatives and the biological activities of which are a function of the parent aldehyde or ketone are the most important properties of thiosemicarbazone class of ligands (hydrazine carbothioamindes). Their metal complexes, especially those containing copper (II) and iron (III) are more active than uncoordinated NNS Schiff base molecular adducts and enhanced biological activity of metal thiosemicarbazones has been under investigation for some time. NNS Schiff base molecular adducts are very good ligands and it has been shown that their biological activity is related to their ability to coordinate to metal centres in enzymes. NNS Schiff base molecular adducts are more active in cell destruction, as well as in the inhibition of DNA synthesis. NNS Schiff base molecular adducts are obtained by condensation of thiosemicarbazide or a substituted thiosemicarbazide at the N (4) position with a suitable aldehyde or ketone.

About this title

About the Author

Prof.Richa Kothari has 17 years of academic and research experience at UG & PG level. She did her Msc.Ph.D(Chemistry)from Jiwaji University Gwalior India and published 20 research papers in reputed journals. She has filed 4 patents & guided 1 Ph.d Scholar. She holds the position of HOD, Deptt. of Chemistry, ITM University, Gwalior, India.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2016
• Language: English
• ISBN 10: 3659880574
• ISBN 13: 9783659880575
• Binding: Paperback
• Number of pages: 76