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Cationic Polymers based Non-viral Gene Carriers: Pharmaceutical Applications of Nano-vectors in Transfection Technology - Softcover
Synopsis
Nucleic acids-based next generation biopharmaceuticals (i.e., oligonucleotides, siRNA) are potential therapeutic agents have ability to cope with various incurable diseases. However, several biological barriers present a challenge for efficient gene delivery. Inception of nanotechnology now offer numerous non-viral vectors that have been fabricated and found capable of transmitting the biopharmaceuticals into the cell and even into specific subcellular compartments like mitochondria. This book illustrates novel chemically modified polyallylamine and polyethylenimine based nano- vectors for enhanced gene delivery. Modification of these polymers using imidazolyl and polysaccharides such as hyaluronic acid, chondroitin sulfate and heparin not only improve cytotoxicity index but also provides site-specificity for cell-type specific gene delivery. Incorporation of targeting moiety minimizes the chance of potential adverse effects and also reduces the amount the amount of dose required to achieve desired therapeutic effects. Recent developments in formulation of efficient drug carriers showed potential to develop gene therapy again diseases like cancer.
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About the Author
Dr. Atul Pathak is a Research Fellow at Immune Disease Institute, Program and Cellular and Molecular Medicine at Children Hospital, Harvard Medical School, Boston, USA. He earned his Ph.D. in Pharmaceutical Science. Dr. Kailash C. Gupta is a director of Indian Institute of Toxicology Research, India.
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Cationic Polymers Based Non-Viral Gene Carriers
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2011
ISBN 10: 3843376190
ISBN 13: 9783843376198
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Cationic Polymers based Non-viral Gene Carriers
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LAP LAMBERT Academic Publishing Feb 2011, 2011
ISBN 10: 3843376190
ISBN 13: 9783843376198
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nucleic acids-based next generation biopharmaceuticals (i.e., oligonucleotides, siRNA) are potential therapeutic agents have ability to cope with various incurable diseases. However, several biological barriers present a challenge for efficient gene delivery. Inception of nanotechnology now offer numerous non-viral vectors that have been fabricated and found capable of transmitting the biopharmaceuticals into the cell and even into specific subcellular compartments like mitochondria. This book illustrates novel chemically modified polyallylamine and polyethylenimine based nano- vectors for enhanced gene delivery. Modification of these polymers using imidazolyl and polysaccharides such as hyaluronic acid, chondroitin sulfate and heparin not only improve cytotoxicity index but also provides site-specificity for cell-type specific gene delivery. Incorporation of targeting moiety minimizes the chance of potential adverse effects and also reduces the amount the amount of dose required to achieve desired therapeutic effects. Recent developments in formulation of efficient drug carriers showed potential to develop gene therapy again diseases like cancer. 156 pp. Englisch. Seller Inventory # 9783843376198
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Cationic Polymers Based Non-Viral Gene Carriers
Published by
VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2011
ISBN 10: 3843376190
ISBN 13: 9783843376198
New
Softcover
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Cationic Polymers Based Non-Viral Gene Carriers
Published by
VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2011
ISBN 10: 3843376190
ISBN 13: 9783843376198
New
Softcover
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Cationic Polymers based Non-viral Gene Carriers
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ISBN 13: 9783843376198
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Pathak AtulDr. Atul Pathak is a Research Fellow at Immune Disease Institute, Program and Cellular and Molecular Medicine at Children Hospital, Harvard Medical School, Boston, USA. He earned his Ph.D. in Pharmaceutical Science. D. Seller Inventory # 5467499
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Cationic Polymers based Non-viral Gene Carriers
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LAP LAMBERT Academic Publishing Feb 2011, 2011
ISBN 10: 3843376190
ISBN 13: 9783843376198
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Taschenbuch. Condition: Neu. Neuware -Nucleic acids-based next generation biopharmaceuticals (i.e., oligonucleotides, siRNA) are potential therapeutic agents have ability to cope with various incurable diseases. However, several biological barriers present a challenge for efficient gene delivery. Inception of nanotechnology now offer numerous non-viral vectors that have been fabricated and found capable of transmitting the biopharmaceuticals into the cell and even into specific subcellular compartments like mitochondria. This book illustrates novel chemically modified polyallylamine and polyethylenimine based nano- vectors for enhanced gene delivery. Modification of these polymers using imidazolyl and polysaccharides such as hyaluronic acid, chondroitin sulfate and heparin not only improve cytotoxicity index but also provides site-specificity for cell-type specific gene delivery. Incorporation of targeting moiety minimizes the chance of potential adverse effects and also reduces the amount the amount of dose required to achieve desired therapeutic effects. Recent developments in formulation of efficient drug carriers showed potential to develop gene therapy again diseases like cancer.Books on Demand GmbH, Überseering 33, 22297 Hamburg 156 pp. Englisch. Seller Inventory # 9783843376198
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Cationic Polymers based Non-viral Gene Carriers : Pharmaceutical Applications of Nano-vectors in Transfection Technology
Published by
LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3843376190
ISBN 13: 9783843376198
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Nucleic acids-based next generation biopharmaceuticals (i.e., oligonucleotides, siRNA) are potential therapeutic agents have ability to cope with various incurable diseases. However, several biological barriers present a challenge for efficient gene delivery. Inception of nanotechnology now offer numerous non-viral vectors that have been fabricated and found capable of transmitting the biopharmaceuticals into the cell and even into specific subcellular compartments like mitochondria. This book illustrates novel chemically modified polyallylamine and polyethylenimine based nano- vectors for enhanced gene delivery. Modification of these polymers using imidazolyl and polysaccharides such as hyaluronic acid, chondroitin sulfate and heparin not only improve cytotoxicity index but also provides site-specificity for cell-type specific gene delivery. Incorporation of targeting moiety minimizes the chance of potential adverse effects and also reduces the amount the amount of dose required to achieve desired therapeutic effects. Recent developments in formulation of efficient drug carriers showed potential to develop gene therapy again diseases like cancer. Seller Inventory # 9783843376198
Quantity: 1 available
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Cationic Polymers based Non-viral Gene Carriers: Pharmaceutical Applications of Nano-vectors in Transfection Technology
Published by
LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3843376190
ISBN 13: 9783843376198
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