HPTLC Method Development and Validation: Analytical Method Development and Validation

 
9783844327359: HPTLC Method Development and Validation: Analytical Method Development and Validation

Simultaneous quantification of Lopinavir and Ritonavir in tablet by HPTLC method was developed and validated .The chromatograms were developed using a mobile phase of Chloroform: 1, 4 - Dioxane (7:3 %v/v) on pre-coated plate of silica gel GF aluminum TLC plate and quantified by densitometric absorbance mode at 210 nm. The Rf value for lopinavir and ritonavir was 0.74 and 0.58 respectively. The linearity of the method was found to be within the concentration range of 160-960 ng/spot for Lopinavir and for Ritonavir, it was 40-240 ng/spot. The lower limits of detection and quantification were 9.56 ng/spot and 28.96 ng/spot for Lopinavir and 6.82 ng/spot and 20.66 ng/spot for Ritonavir. The method was also validated for precision, specificity and recovery. This developed method was used to analyze fixed-dose tablet (Lopimune, Cipla Ltd) sample of Lopinavir and Ritonavir.

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At presently working as senior assistant professor at Faculty of Pharmacy, Dharmsinh Desai University, Nadiad, Gujarat, India. I have completed my Ph.D. under the guidance of Dr. T. Y. Pasha and B. N. Suhagia from Saurashtra University, Rajkot,in December- 2012. I have 1 national and 6 international papers published.I have presented 5 papers.

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Book Description Book Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | Analytical Method Development and Validation | Simultaneous quantification of Lopinavir and Ritonavir in tablet by HPTLC method was developed and validated .The chromatograms were developed using a mobile phase of Chloroform: 1, 4 - Dioxane (7:3 %v/v) on pre-coated plate of silica gel GF aluminum TLC plate and quantified by densitometric absorbance mode at 210 nm. The Rf value for lopinavir and ritonavir was 0.74 and 0.58 respectively. The linearity of the method was found to be within the concentration range of 160-960 ng/spot for Lopinavir and for Ritonavir, it was 40-240 ng/spot. The lower limits of detection and quantification were 9.56 ng/spot and 28.96 ng/spot for Lopinavir and 6.82 ng/spot and 20.66 ng/spot for Ritonavir. The method was also validated for precision, specificity and recovery. This developed method was used to analyze fixed-dose tablet (Lopimune, Cipla Ltd) sample of Lopinavir and Ritonavir. | Format: Paperback | Language/Sprache: english | 64 pp. Bookseller Inventory # K9783844327359

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Book Description LAP Lambert Academic Publishing. Paperback. Book Condition: New. Paperback. 64 pages. Dimensions: 8.7in. x 5.9in. x 0.1in.Simultaneous quantification of Lopinavir and Ritonavir in tablet by HPTLC method was developed and validated . The chromatograms were developed using a mobile phase of Chloroform: 1, 4 - Dioxane (7: 3 vv) on pre-coated plate of silica gel GF aluminum TLC plate and quantified by densitometric absorbance mode at 210 nm. The Rf value for lopinavir and ritonavir was 0. 74 and 0. 58 respectively. The linearity of the method was found to be within the concentration range of 160-960 ngspot for Lopinavir and for Ritonavir, it was 40-240 ngspot. The lower limits of detection and quantification were 9. 56 ngspot and 28. 96 ngspot for Lopinavir and 6. 82 ngspot and 20. 66 ngspot for Ritonavir. The method was also validated for precision, specificity and recovery. This developed method was used to analyze fixed-dose tablet (Lopimune, Cipla Ltd) sample of Lopinavir and Ritonavir. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783844327359

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Rajnikant Mardia
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Book Description LAP Lambert Academic Publishing Nov 2015, 2015. Taschenbuch. Book Condition: Neu. Neuware - Simultaneous quantification of Lopinavir and Ritonavir in tablet by HPTLC method was developed and validated .The chromatograms were developed using a mobile phase of Chloroform: 1, 4 - Dioxane (7:3 %v/v) on pre-coated plate of silica gel GF aluminum TLC plate and quantified by densitometric absorbance mode at 210 nm. The Rf value for lopinavir and ritonavir was 0.74 and 0.58 respectively. The linearity of the method was found to be within the concentration range of 160-960 ng/spot for Lopinavir and for Ritonavir, it was 40-240 ng/spot. The lower limits of detection and quantification were 9.56 ng/spot and 28.96 ng/spot for Lopinavir and 6.82 ng/spot and 20.66 ng/spot for Ritonavir. The method was also validated for precision, specificity and recovery. This developed method was used to analyze fixed-dose tablet (Lopimune, Cipla Ltd) sample of Lopinavir and Ritonavir. 64 pp. Englisch. Bookseller Inventory # 9783844327359

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Book Description LAP Lambert Academic Publishing Nov 2015, 2015. Taschenbuch. Book Condition: Neu. Neuware - Simultaneous quantification of Lopinavir and Ritonavir in tablet by HPTLC method was developed and validated .The chromatograms were developed using a mobile phase of Chloroform: 1, 4 - Dioxane (7:3 %v/v) on pre-coated plate of silica gel GF aluminum TLC plate and quantified by densitometric absorbance mode at 210 nm. The Rf value for lopinavir and ritonavir was 0.74 and 0.58 respectively. The linearity of the method was found to be within the concentration range of 160-960 ng/spot for Lopinavir and for Ritonavir, it was 40-240 ng/spot. The lower limits of detection and quantification were 9.56 ng/spot and 28.96 ng/spot for Lopinavir and 6.82 ng/spot and 20.66 ng/spot for Ritonavir. The method was also validated for precision, specificity and recovery. This developed method was used to analyze fixed-dose tablet (Lopimune, Cipla Ltd) sample of Lopinavir and Ritonavir. 64 pp. Englisch. Bookseller Inventory # 9783844327359

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Mardia Rajnikant, Pasha T y, Suhagia B N
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Book Description LAP Lambert Academic Publishing, United States, 2015. Paperback. Book Condition: New. Language: English . Brand New Book ***** Print on Demand *****.Simultaneous quantification of Lopinavir and Ritonavir in tablet by HPTLC method was developed and validated .The chromatograms were developed using a mobile phase of Chloroform: 1, 4 - Dioxane (7:3 v/v) on pre-coated plate of silica gel GF aluminum TLC plate and quantified by densitometric absorbance mode at 210 nm. The Rf value for lopinavir and ritonavir was 0.74 and 0.58 respectively. The linearity of the method was found to be within the concentration range of 160-960 ng/spot for Lopinavir and for Ritonavir, it was 40-240 ng/spot. The lower limits of detection and quantification were 9.56 ng/spot and 28.96 ng/spot for Lopinavir and 6.82 ng/spot and 20.66 ng/spot for Ritonavir. The method was also validated for precision, specificity and recovery. This developed method was used to analyze fixed-dose tablet (Lopimune, Cipla Ltd) sample of Lopinavir and Ritonavir. Bookseller Inventory # AAV9783844327359

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