Biocompatible Nonionic Microemulsions: Formulation and Characterisation Approach - Softcover

Djekic, Ljiljana

Softcover

ISBN 10: 3845434678 ISBN 13: 9783845434674

Publisher: LAP LAMBERT Academic Publishing, 2012

Synopsis

Rigorous regulations in pharmaceutical industry urge for more sophisticated approaches that could be used for design and characterisation of drug delivery systems. Microemulsions are promissing carriers of active pharmaceutical ingredients. Researchers in this field are focused on development of biocompatible microemulsions stabilised by nonionic surfactants mixtures. The efficiency of tensides mixtures for microemulsion formation, their microstructure, solubilisation capacity, and mechanisms of drug release are scarcely investigated. This book provides a new formulation strategy of microemulsions based on multicomponent surfactant mixtures by conducting phase behaviour study and developing arteficial neural network models suitable for microemulsion area modeling. There is also demenstrated evaluation of colloidal microstructure, drug solubilisation capacity, and in vitro drug release mechanism of a model drug ibuprofen. The comprehensive approach for nonionic microemulsion carriers design may be useful to formulators in pharmaceutical, cosmetic and food industries as well as for anyone else who are interested in research and application of such complex systems.

About this title

About the Author

Ljiljana M. Djekic, Dr: Studied Faculty of Pharmacy at University of Belgrade. Docent at Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade. Research interests: novel pharmaceutical dosage forms, formulation approaches for drug absorption enhancement, colloidal drug carriers, nanopharmaceutics.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2012
• Language: English
• ISBN 10: 3845434678
• ISBN 13: 9783845434674
• Binding: Paperback
• Number of pages: 212