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Studies on Andrographolide from Andrographis paniculata: Extraction, Development and Characterization of AR K562 cell lines - Softcover
Synopsis
Andrographolide is the main diterpenoid lactone contained in the leaves of Andrographis paniculata. This bioactive component has multifunctional medicinal properties such as activity against fever, dysentery, diarrhoea, inflammation, cancer and sore throat as well as immune disorder. No solvent is ideal for the extraction of Andrographolide, however we can consider 60% methanol for the model development. Cancer is the largest single cause of death in both men and women, claiming over 6 million each year in the world. CML accounts for about 20% cases of adult and childhood leukemia. Andrographolide acts by targeting the tyrosine kinase activity of BCR-ABL which represents a very promising therapeutic strategy in chronic myeloid leukemia (CMML). In the present study, we focused on amplifying the ABL kinase domain sequence and b2a2 junction domain sequence and tried to find out the sequence difference between normal K562 cells and AR-K562 cells .for this we developed resistant cell lines against Andrographolide by gradual increase in the in the concentration of Andrographolide (1nm to 1um), the morphological features were studied in phase contrast microscopy.
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About the Author
Sumanjali Avanigadda is research scholar under the guidance of Dr. Meena Vangalapati, published three research papers. Dr. Meena Vangalapati M.Tech, Ph.D, Associate Professor from Department of Chemical Engineering, Andhra University, Visakhapatnam, India. She had teaching experience of 10 years and published 35 more research papers.
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- PublisherLAP LAMBERT Academic Publishing
- Publication date2011
- ISBN 10 3846505536
- ISBN 13 9783846505533
- BindingPaperback
- LanguageEnglish
- Number of pages140
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Studies on Andrographolide from Andrographis paniculata
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LAP LAMBERT Academic Publishing Sep 2011, 2011
ISBN 10: 3846505536
ISBN 13: 9783846505533
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Andrographolide is the main diterpenoid lactone contained in the leaves of Andrographis paniculata. This bioactive component has multifunctional medicinal properties such as activity against fever, dysentery, diarrhoea, inflammation, cancer and sore throat as well as immune disorder. No solvent is ideal for the extraction of Andrographolide, however we can consider 60% methanol for the model development. Cancer is the largest single cause of death in both men and women, claiming over 6 million each year in the world. CML accounts for about 20% cases of adult and childhood leukemia. Andrographolide acts by targeting the tyrosine kinase activity of BCR-ABL which represents a very promising therapeutic strategy in chronic myeloid leukemia (CMML). In the present study, we focused on amplifying the ABL kinase domain sequence and b2a2 junction domain sequence and tried to find out the sequence difference between normal K562 cells and AR-K562 cells .for this we developed resistant cell lines against Andrographolide by gradual increase in the in the concentration of Andrographolide (1nm to 1um), the morphological features were studied in phase contrast microscopy. 140 pp. Englisch. Seller Inventory # 9783846505533
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Studies on Andrographolide from Andrographis paniculata : Extraction, Development and Characterization of AR K562 cell lines
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LAP LAMBERT Academic Publishing, 2011
ISBN 10: 3846505536
ISBN 13: 9783846505533
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Andrographolide is the main diterpenoid lactone contained in the leaves of Andrographis paniculata. This bioactive component has multifunctional medicinal properties such as activity against fever, dysentery, diarrhoea, inflammation, cancer and sore throat as well as immune disorder. No solvent is ideal for the extraction of Andrographolide, however we can consider 60% methanol for the model development. Cancer is the largest single cause of death in both men and women, claiming over 6 million each year in the world. CML accounts for about 20% cases of adult and childhood leukemia. Andrographolide acts by targeting the tyrosine kinase activity of BCR-ABL which represents a very promising therapeutic strategy in chronic myeloid leukemia (CMML). In the present study, we focused on amplifying the ABL kinase domain sequence and b2a2 junction domain sequence and tried to find out the sequence difference between normal K562 cells and AR-K562 cells .for this we developed resistant cell lines against Andrographolide by gradual increase in the in the concentration of Andrographolide (1nm to 1um), the morphological features were studied in phase contrast microscopy. Seller Inventory # 9783846505533
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Studies on Andrographolide from Andrographis paniculata
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Avanigadda SumanjaliSumanjali Avanigadda is research scholar under the guidance of Dr. Meena Vangalapati, published three research papers. Dr. Meena Vangalapati M.Tech, Ph.D, Associate Professor from Department of Chemical Engineerin. Seller Inventory # 5495267
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Studies on Andrographolide from Andrographis paniculata
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Taschenbuch. Condition: Neu. Neuware -Andrographolide is the main diterpenoid lactone contained in the leaves of Andrographis paniculata. This bioactive component has multifunctional medicinal properties such as activity against fever, dysentery, diarrhoea, inflammation, cancer and sore throat as well as immune disorder. No solvent is ideal for the extraction of Andrographolide, however we can consider 60% methanol for the model development. Cancer is the largest single cause of death in both men and women, claiming over 6 million each year in the world. CML accounts for about 20% cases of adult and childhood leukemia. Andrographolide acts by targeting the tyrosine kinase activity of BCR-ABL which represents a very promising therapeutic strategy in chronic myeloid leukemia (CMML). In the present study, we focused on amplifying the ABL kinase domain sequence and b2a2 junction domain sequence and tried to find out the sequence difference between normal K562 cells and AR-K562 cells .for this we developed resistant cell lines against Andrographolide by gradual increase in the in the concentration of Andrographolide (1nm to 1um), the morphological features were studied in phase contrast microscopy.Books on Demand GmbH, Überseering 33, 22297 Hamburg 140 pp. Englisch. Seller Inventory # 9783846505533
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Studies on Andrographolide from Andrographis paniculata: Extraction, Development and Characterization of AR K562 cell lines
Published by
LAP LAMBERT Academic Publishing, 2011
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ISBN 13: 9783846505533
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