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The study was designed for phytochemical investigations of ethanolic extract of bark and leaf of Swietenia mahagoni belonging to the family of Meliaceae and evaluation of their biological activities with the special emphasis on analgesic, anti-inflammatory, anti-microbial and cytotoxic screening in different animal model. Phytochemical investigations were done by extensive analysis with high resolution proton NMR spectroscopic data. The ethanol extract of stem bark was partitioned between pet-ether, dichloromethane and methanol fractions. Chromatographic isolation of dichloromethane fraction using column chromatography followed by preparative TLC afforded tetranortriterpenoid compound. Ethanol extract and different fractions showed significant analgesic and anti-inflammatory potential.From the bio-assay of different fractions and extract, significant cytotoxic properties were evaluated whereas mild to moderate antimicrobial activity was found in this study.
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Mohammad Ahsanul Akbar is a Lecturer of the Department of Clinical Pharmacy and Pharmacology, University of Dhaka, Bangladesh and also a PhD student in the Department of Pharmaceutics, University of Florida, USA. His research interest is on molecular pharmacology, gene therapy and plant related bio-activity investigations.
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- PublisherLAP LAMBERT Academic Publishing
- Publication date2012
- ISBN 10 3848447665
- ISBN 13 9783848447664
- BindingPaperback
- Number of pages128
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study was designed for phytochemical investigations of ethanolic extract of bark and leaf of Swietenia mahagoni belonging to the family of Meliaceae and evaluation of their biological activities with the special emphasis on analgesic, anti-inflammatory, anti-microbial and cytotoxic screening in different animal model. Phytochemical investigations were done by extensive analysis with high resolution proton NMR spectroscopic data. The ethanol extract of stem bark was partitioned between pet-ether, dichloromethane and methanol fractions. Chromatographic isolation of dichloromethane fraction using column chromatography followed by preparative TLC afforded tetranortriterpenoid compound. Ethanol extract and different fractions showed significant analgesic and anti-inflammatory potential.From the bio-assay of different fractions and extract, significant cytotoxic properties were evaluated whereas mild to moderate antimicrobial activity was found in this study. 128 pp. Englisch. Seller Inventory # 9783848447664
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Investigations of biological principles of Swietenia mahagoni : Family: Meliaceae
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Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The study was designed for phytochemical investigations of ethanolic extract of bark and leaf of Swietenia mahagoni belonging to the family of Meliaceae and evaluation of their biological activities with the special emphasis on analgesic, anti-inflammatory, anti-microbial and cytotoxic screening in different animal model. Phytochemical investigations were done by extensive analysis with high resolution proton NMR spectroscopic data. The ethanol extract of stem bark was partitioned between pet-ether, dichloromethane and methanol fractions. Chromatographic isolation of dichloromethane fraction using column chromatography followed by preparative TLC afforded tetranortriterpenoid compound. Ethanol extract and different fractions showed significant analgesic and anti-inflammatory potential.From the bio-assay of different fractions and extract, significant cytotoxic properties were evaluated whereas mild to moderate antimicrobial activity was found in this study. Seller Inventory # 9783848447664
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Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Akbar Mohammad AhsanulMohammad Ahsanul Akbar is a Lecturer of the Department of Clinical Pharmacy and Pharmacology, University of Dhaka, Bangladesh and also a PhD student in the Department of Pharmaceutics, University of Florida, USA. Seller Inventory # 5522896
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