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- ISBN 10 3954046717
- ISBN 13 9783954046713
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Novel Approaches to Optical Activity Measurements
Published by
Cuvillier Mrz 2014
(2014)
ISBN 10: 3954046717
ISBN 13: 9783954046713
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Chiral molecules exist in two geometric configurations of their atoms with mirror-image symmetry, which are called enantiomers. Many natural and organic molecules are chiral, such as peptides, enzymes, many amino acids or proteins. Despite similar physical and chemical properties, enantiomers may have very different biochemical and physiological effects being of great interest for the development of new pharmaceutically active compounds. Optical methods provide a direct means of distinguishing the enantiomers due to their differential interaction with circularly polarized light. This difference is generally referred to as Optical Activity.This book presents and evaluates new optical methods for the detection of Optical Activity in refraction, absorption and scattering. Beside different concepts for a Chiral Refractometer allowing the measurement of Optical Activity in microfluidic volumes the first realization of a VCD spectrometer based on a Quantum Cascade Laser is shown. It enables Optical Activity studies in strongly absorbing solvents like water. Finally differential scattering experiments are used for the characterization of chiral colloids, which can act as model systems for chiral molecules. 138 pp. Englisch. Seller Inventory # 9783954046713
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Novel Approaches to Optical Activity Measurements
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Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Chiral molecules exist in two geometric configurations of their atoms with mirror-image symmetry, which are called enantiomers. Many natural and organic molecules are chiral, such as peptides, enzymes, many amino acids or proteins. Despite similar physical and chemical properties, enantiomers may have very different biochemical and physiological effects being of great interest for the development of new pharmaceutically active compounds. Optical methods provide a direct means of distinguishing the enantiomers due to their differential interaction with circularly polarized light. This difference is generally referred to as Optical Activity.This book presents and evaluates new optical methods for the detection of Optical Activity in refraction, absorption and scattering. Beside different concepts for a Chiral Refractometer allowing the measurement of Optical Activity in microfluidic volumes the first realization of a VCD spectrometer based on a Quantum Cascade Laser is shown. It enables Optical Activity studies in strongly absorbing solvents like water. Finally differential scattering experiments are used for the characterization of chiral colloids, which can act as model systems for chiral molecules. Seller Inventory # 9783954046713
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Novel Approaches to Optical Activity Measurements
Published by
Cuvillier Verlag
(2014)
ISBN 10: 3954046717
ISBN 13: 9783954046713
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Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. KlappentextrnrnChiral molecules exist in two geometric configurations of their atoms with mirror-image symmetry, which are called enantiomers. Many natural and organic molecules are chiral, such as peptides, enzymes, many amino acids or proteins. Seller Inventory # 68826027
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