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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The encapsulation mechanism of \*rINF- -2b in lipid, carbohydrate and protein based microspheres to achieve high encapsulation efficiency and protein loading capacity. \*rINF- -2b is a fragile molecule and encapsulation requires in addition the preservation of their structural integrity and functionality. We estimated that \*rINF- -2b-Pt-GMs-15 offered sustained release of protein over two weeks and released 95.01±4.23% of \*rINF- -2b. The stability study assessment by gel electrophoresis and circular dichroism confirmed post translation structural integrity of \*rINF- -2b in \*rINF- -2b-Pt-GMs-15 nanoformulation. In vitro therapeutic efficacy testing of optimized formulation further provided compelling evidence with enhanced cytotoxicity and low IC50 in SKOV3 cells. Therefore protamine sulphate coated microspheres may potentially be used for sustained delivery of \*rINF- -2b and warrants in depth in vivo study to scale up the technology for clinical intervention. 88 pp. Englisch. Seller Inventory # 9786206791058
Quantity: 2 available
Seller: AHA-BUCH GmbH, Einbeck, Germany
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The encapsulation mechanism of \*rINF- -2b in lipid, carbohydrate and protein based microspheres to achieve high encapsulation efficiency and protein loading capacity. \*rINF- -2b is a fragile molecule and encapsulation requires in addition the preservation of their structural integrity and functionality. We estimated that \*rINF- -2b-Pt-GMs-15 offered sustained release of protein over two weeks and released 95.01±4.23% of \*rINF- -2b. The stability study assessment by gel electrophoresis and circular dichroism confirmed post translation structural integrity of \*rINF- -2b in \*rINF- -2b-Pt-GMs-15 nanoformulation. In vitro therapeutic efficacy testing of optimized formulation further provided compelling evidence with enhanced cytotoxicity and low IC50 in SKOV3 cells. Therefore protamine sulphate coated microspheres may potentially be used for sustained delivery of \*rINF- -2b and warrants in depth in vivo study to scale up the technology for clinical intervention. Seller Inventory # 9786206791058
Quantity: 1 available
Seller: moluna, Greven, Germany
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The encapsulation mechanism of *rINF- -2b in lipid, carbohydrate and protein based microspheres to achieve high encapsulation efficiency and protein loading capacity. *rINF- -2b is a fragile molecule and encapsulation requires in addition the preservation o. Seller Inventory # 1240487977
Quantity: Over 20 available