Synopsis
A Visible Spectrophotometric method has been developed and validated for the quantitative measurement of Bempedoic acid in bulk and tablet dosage forms. The process is based on the production of a colored complex in the presence of Ferric chloride between Bempedoic acid and MBTH (3-methyl-2-benzothiazolinone Hydrazone). At 663 nm, the colored complex was spectrophotometrically measured. The correlation coefficient (r2) of 0.999 revealed that the approach is linear in the concentration range of 10-60 µg/mL. It was discovered that the limits of detection (LOD) and quantitation (LOQ) were 2.169 µg/mL and 6.572 µg/mL, respectively. For both intra-day and inter-day precision studies, the approach was proven to be precise with a percent relative standard deviation (%RSD) less than 2.0%. Recovery experiments were used to assess the method's accuracy, and it was discovered that the average percentage of recovery fell between 98.0 and 102.0%. The results of the suggested approach were compared to those of the reference method for the accurate determination of Bempedoic acid in tablet dosage forms.
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New Method Development and Validation of Bempedoic Acid
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New Method Development and Validation of Bempedoic Acid
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NEW METHOD DEVELOPMENT AND VALIDATION OF BEMPEDOIC ACID
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A Visible Spectrophotometric method has been developed and validated for the quantitative measurement of Bempedoic acid in bulk and tablet dosage forms. The process is based on the production of a colored complex in the presence of Ferric chloride between Bempedoic acid and MBTH (3-methyl-2-benzothiazolinone Hydrazone). At 663 nm, the colored complex was spectrophotometrically measured. The correlation coefficient (r2) of 0.999 revealed that the approach is linear in the concentration range of 10-60 µg/mL. It was discovered that the limits of detection (LOD) and quantitation (LOQ) were 2.169 µg/mL and 6.572 µg/mL, respectively. For both intra-day and inter-day precision studies, the approach was proven to be precise with a percent relative standard deviation (%RSD) less than 2.0%. Recovery experiments were used to assess the method's accuracy, and it was discovered that the average percentage of recovery fell between 98.0 and 102.0%. The results of the suggested approach were compared to those of the reference method for the accurate determination of Bempedoic acid in tablet dosage forms.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 76 pp. Englisch. Seller Inventory # 9786208223564
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NEW METHOD DEVELOPMENT AND VALIDATION OF BEMPEDOIC ACID
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ISBN 13: 9786208223564
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A Visible Spectrophotometric method has been developed and validated for the quantitative measurement of Bempedoic acid in bulk and tablet dosage forms. The process is based on the production of a colored complex in the presence of Ferric chloride between Bempedoic acid and MBTH (3-methyl-2-benzothiazolinone Hydrazone). At 663 nm, the colored complex was spectrophotometrically measured. The correlation coefficient (r2) of 0.999 revealed that the approach is linear in the concentration range of 10-60 µg/mL. It was discovered that the limits of detection (LOD) and quantitation (LOQ) were 2.169 µg/mL and 6.572 µg/mL, respectively. For both intra-day and inter-day precision studies, the approach was proven to be precise with a percent relative standard deviation (%RSD) less than 2.0%. Recovery experiments were used to assess the method's accuracy, and it was discovered that the average percentage of recovery fell between 98.0 and 102.0%. The results of the suggested approach were compared to those of the reference method for the accurate determination of Bempedoic acid in tablet dosage forms. Seller Inventory # 9786208223564
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NEW METHOD DEVELOPMENT AND VALIDATION OF BEMPEDOIC ACID
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Taschenbuch. Condition: Neu. NEW METHOD DEVELOPMENT AND VALIDATION OF BEMPEDOIC ACID | Sridevi Ranjitha Karanam (u. a.) | Taschenbuch | Englisch | 2024 | LAP LAMBERT Academic Publishing | EAN 9786208223564 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu. Seller Inventory # 130391370
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